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The recent expansion in genome data and the parallel increase in cheap computing power has placed the bioinformatics exploration of pathogen genomes centre stage for vaccine researchers. Discussing the ways in which bioinformatics can contribute to improved vaccine development, Bioinformatics for Vaccinology shows how bioinformatic techniques can solve key problems from vaccinology and immunology. The only book to address the area of bioinformatics as applied to rational vaccine design, this text is written to appeal to both the bioinformatician and the immunologist.

 

Aus dem Inhalt

CONTENTS

 

Preface

 

Acknowledgements

 

Exordium: Vaccines: a Very, Very Short Introduction

 

1 Vaccines: Their Place in History

 

2 Vaccines: Need and Opportunity

 

3 Vaccines: How They Work

 

4 Vaccines: Data and Databases

 

5 Vaccines: Data Driven Prediction of Binders, Epitopes and Immunogenicity

 

6 Vaccines: Structural Approaches

 

7 Vaccines: Computational Solutions

 

Index