opens in new tab
Antibody engineering
0 ratings
Search for this author
more...
Year:
[2018]
Publisher:
Rijeka, Croatia, InTech
Media group:
Ausleihbestand
Branch | Locations | Status | Reservations | Due date | Barcode | Floor plan | Lending note |
Branch:
Hauptstelle
|
Locations:
ZB-90
341
|
Status:
available
|
Reservations:
0
|
Due date:
|
Barcode:
00301477
|
Floor plans:
Floor plan
|
Lending note:
|
Antibody Engineering comprises in vitro selection and modification of human antibodies including humanization of mouse antibodies for therapy, diagnosis, and research. This book comprises an overview about the generation of antibody diversity and essential techniques in antibody engineering: construction of immune, naive and synthetic libraries, all available in vitro display methods, humanization by chain shuffling, affinity maturation techniques, de novo synthesis of antibody genes, colony assays for library screening, construction of scFvs from hybridomas, and purification of monoclonal antibodies by exclusion chromatography. In addition, other topics that are discussed in this book are application and mechanism of single domain antibodies, structural diversity of antibodies, immune-mediated skin reactions induced by TNF-alpha recombinant antibodies, and bioinformatic approaches to select pathogen-derived peptide sequences for antibody targets.
0 ratings
0 ratings
0 ratings
0 ratings
0 ratings
Search for this author
Statement of Responsibility:
edited by Thomas Böldicke
Year:
[2018]
Publisher:
Rijeka, Croatia, InTech
Articles:
Go to this article
opens in new tab
Classification:
Search for this systematic
ZB-90
Search for this subject type
ISBN:
9789535138259
Description:
XI, 299 Seiten, Illustrationen, Diagramme
Language:
Englisch
Media group:
Ausleihbestand