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Targeted protein degradation
methods and protocols
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Year:
[2021]
Publisher:
New York, NY, Humana Press, Springer Science+Business Media, LLC, part of Springer Nature
Media group:
Dauerleihe
Branch | Locations | Status | Reservations | Due date | Barcode | Floor plan | Lending note |
Branch:
Dauerleihe
|
Locations:
ME-20
108
|
Status:
borrowed
|
Reservations:
0
|
Due date:
1/1/2199
|
Barcode:
00310280
|
Floor plans:
Floor plan
|
Lending note:
|
This volume contains a collection of innovative techniques for studying targeted protein degradation. Chapters guide readers through heterobifunctional proteolysis-targeting chimeras (PROTACs) approaches, E3 ligase, E3 ligase-induced ubiquitylation, proteomic approaches, novel degrader molecules, molecular glue, and stabilize binding interaction between a target and E3 ubiquitin ligase. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.
Authoritative and cutting-edge, Targeted Protein Degradation: Methods and Protocols aims to ensure successful results in this emerging field of drug discovery.
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Statement of Responsibility:
edited by Angela M. Cacace, Christopher M. Hickey, and Miklós Békés, Platform Biology, Arvinas Inc., New Haven CT, USA
Year:
[2021]
Publisher:
New York, NY, Humana Press, Springer Science+Business Media, LLC, part of Springer Nature
Articles:
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ISBN:
9781071616642
ISBN (2nd):
1071616641
Description:
xi, 351 Seiten, Diagramme, Illustrationen
Language:
Englisch
Media group:
Dauerleihe