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The Myc/Max/Mad transcription factor network

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Year: 2006
Publisher: Berlin [u.a.], Springer
Series: Current topics in microbiology and immunology; 302
Media group: Serien
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Content

Inhaltsverzeichnise (Kurzversion) - Table of Contents (short version)
 
Preface
Making Myc
 Transcriptionsl Activation by the Myc Oncoprotein
 Mechanisms of Transcriptional Repression by Myc
 The Mad Side of the Max Network: Antagonising the Function of Myc and More
 Structural Aspects of Interactions within the Myc/Max/Mad Network
 Myc Target Transcriptomes
 c-Myc, Genome Instability, and Tumorigenesis: The Devil is in the Details
 Lessons Learned from Myc/Max/Mad Knockout Mice
 Myc/Max/Mad in Invertebrates. The Evolution of the Max Network
 The Mix Network: Evidence for a Parallel Max-like Transcriptional Network that Regulates Energy Metabolism
 Subject Index
 
proliferation; apoptosis; differentiation; growth; metabolism; signal transduction
 
Beschreibung
The Myc/Mad/Mad network is defined by, and functions through, the interactions between individual Myc and Mad family proteins with Max as well as by interactions between Myc and Mad family proteins with higher order co-repressor and co-activator complexes. The chapters included in this volume illustrate the complexities of the Myc/Max/Mad network and how its functions impinge on fundamental biological processes through regulation of transcription.

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Statement of Responsibility: R. N. Eisenman (Ed.)
Year: 2006
Publisher: Berlin [u.a.], Springer
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Classification: Search for this systematic ZB-90, MB-40
Subject type: Search for this subject type Sammelwerke
ISBN: 3540239685
Description: VII, 282 S. : Ill., graph. Darst.
Series: Current topics in microbiology and immunology; 302
Tags: Mikrobiologie; Medizinische Mikrobiologie; Immunbiologie; Immunology; Zellbiologie
Participating parties: Search for this character Eisenman, Robert N. [Hrsg.]
Language: englisch||
Footnote: Literaturangaben
Media group: Serien