Description
The third edition of the landmark text Recombinant DNA offers an authoritative, accessible, and engaging introduction to modern, genomecentered biology from its foremost practitioners. The new edition explores core concepts in molecular biology in a contemporary inquirybased context, building its coverage around the most relevant and exciting examples of current research and landmark experiments that redefined our understanding of DNA. As a result, students learn in a compelling way how working scientists make real highimpact discoveries.
The first chapters provide an introduction to the fundamental concepts of genetics and genomics, an inside look at the Human Genome Project, bioinformatic and experimental techniques for largescale genomic studies, and a survey of epigenetics and RNA interference. The final chapters cover the quest to identify diseasecausing genes, the genetic basis of cancer, and DNA fingerprinting and forensics. In these chapters the authors provide examples of practical applications in human medicine, and discuss the future of human genetics and genomics projects.
Contents
FOUNDATIONS OF DNA
Overview
1. DNA Is the Primary Genetic Material
2. Information Flow from DNA to Protein
3. Control of Gene Expression
4. Basic Tools of Recombinant DNA
5. Fundamental Features of Eukaryotic Genes
6. A New Toolbox for Recombinant DNA
7. Mobile DNA Sequences in the Genome
8. Epigenetic Modifications of the Genome
9. RNAi Regulates Gene Action
FOUNDATIONS OF GENOMICS
Overview
10. Fundamentals of Whole-Genome Sequencing
11. How the Human Genome Was Sequenced
ANALYZING GENOMES
Overview
12. Comparing and Analyzing Genomes
13. From Genome Sequence to Gene Function
HUMAN GENOMICS
Overview
14. Finding Human Disease Genes
15. Understanding the Genetic Basis of Cancer
16. DNA Fingerprinting and Forensics
Figure Credits
Index
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Statement of Responsibility:
James D. Watson ; Richard M. Myers ; Amy A. Caudy ; Jan A. Witkowski
Year:
2007
Publisher:
New York, Freeman
Articles:
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Classification:
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GE-30, GE-40
Subject type:
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Lehrbücher
ISBN:
9780716728665
Description:
3. edition, XXII, 474 S. : Ill., graph. Darst.
Language:
englisch||
Footnote:
Literaturangaben
Media group:
Ausleihbestand