Contents
Note from the Publisher
Preface to the First Edition
John Cairns, Gunther S. Stent, James D. Watson
Preface to the Expanded Edition
John Cairns
I. ORIGINS OF MOLECULAR BIOLOGY
Introduction: Waiting for the Paradox
Gunther S. Stent
A Physicist Looks at Biology
Max Delbrück
Biochemical Genetics: Some Recollections
George W. Beadle
The Target Theory
K.G. Zimmer
High Energy Phosphate Bonds: Optional or Obligatory?
Herman M. Kalckar
II. THE PHAGE RENAISSANCE
Bacteriophage: One-Step Growth
Emory L. Ellis
Electron Microscopy of Phages
Thomas F. Anderson
The Eclipse in the Bacteriophage Life Cycle
A.H. Doermann
The Prophage and I
André Lwoff
The Injection of DNA into Cells by Phage
A.D. Hershey
Transfer of Parental Material to Progeny
Lloyd M. Kozloff
Electron Microscopy of Developing Bacteriophage
Edward Kellenberger
III. PHAGE GENETICS
Phenotypic Mixing
Aaron Novick
Mating Theory
N. Visconti
On the Physical Basis of Genetic Structure in Bacteriophage
A.D. Kaiser
Adventures in the rII Region
Seymour Benzer
Conditional Lethals
R.S. Edgar
IV. BACTERIAL GENETICS
Mutations of Bacteria and of Bacteriophage
S.E. Luria
Gene, Transforming Principle, and DNA
Rollin D. Hotchkiss
Sexual Differentiation in Bacteria
William Hayes
Bacterial Conjugation
Elie L. Wollman
Story and Structure of the ? Transducing Phage
J. Weigle
V. DNA
Growing Up in the Phage Group
J.D. Watson
Demonstration of the Semiconservative Mode of DNA Duplication
Matthew Meselson and Franklin W. Stahl
The Autoradiography of DNA
John Cairns
?x: Multum in Parvo
Robert L. Sinsheimer
The Relation between Nuclear and Cellular Division in Escherichia coli
Ole Maaløe
VI. RAMIFICATIONS OF MOLECULAR BIOLOGY
The Mammalian Cell
T.T. Puck
The Plaque Technique and the Development of Quantitative Animal Virology
Renato Dulbecco
Quantitatitve Tumor Virology
H. Rubin
The Natural Selection Theory of Antibody Formation; Ten Years Later
Niels K. Jerne
Cybernetics of the Insect Optomotor Response
Werner E. Reichardt
Teminal Redundancy, or Alls Well that Ends Well
George Streisinger
VII. REPRINTS
How Molecular Biology Started
John C. Kendrew
Reprinted from Scientific American, March 1967
That Was the Molecular Biology That Was
Gunther S. Stent
Reprinted from Science, April 26, 1968
Max Delbrück, 19061981
Gunther S. Stent
Reprinted from Genetics, May 1982
Timeline
Photo Gallery
Related Products
Phage and the Origins of Molecular Biology
(Expanded Edition) [Paper]
Description
This hugely influential book, published in 1966 as a 60th birthday tribute to Max Delbrück, is now republished as The Centennial Edition. On first publication, the book was hailed as [introducing] into the literature of science, for the first time, a selfconscious historical element in which the participants in scientific discovery engage in writing their own chronicle. As such, it is an important document in the history of biology... (Journal of History of Biology). And in another review it was described as required reading for every student of experimental biology...[who] will sense the smell and rattle of the laboratory (Bioscience). The book was a formative influence on many of todays leading scientists.