Branch	Locations	Status	Reservations	Due date	Barcode	Floor plan	Lending note
Branch: Hauptstelle	Locations: ME-40 17	Status: available	Reservations: 0	Due date:	Barcode: 00297887	Floor plans: Floor plan	Lending note:

Genetic Association Studies is designed for students of public health, epidemiology, and the health sciences, covering the main principles of molecular genetics, population genetics, medical genetics, epidemiology and statistics. It presents a balanced view of genetic associations with coverage of candidate gene studies as well as genome-wide association studies. All aspects of a genetic association study are included, from the lab to analysis and interpretation of results, but also bioinformatics approaches to causality assessment. The role of the environment in genetic disease is also highlighted. Genetic Association Studies will enable readers to understand and critique genetic association studies and set them on the way to designing, executing, analyzing, interpreting, and reporting their own.

 

Features

 

Focuses on two types of genetic association studies: candidate gene studies and genomewide association studies

A non-mathematical approach to explain data analysis methods

Coverage of genotyping methods

Inclusion of a post-GWAS bioinformatics approach to analysing statistical results

Consideration of the environment as an important player in disease genetics

Includes the use of association studies in medical practice and genetic risk profiling

TOC:

1. Primer on Molecular Genetics

2. Primer on Medical Genetics

3. Primer on Population Genetics

4. Epidemiologic Principles and Genetic Association Studies

5. Environmental Epidemiology in the Context of Genetic Epidemiology

6. Elementary Statistical Concepts

7. Genotyping Methods and Errors

8. Candidate Gene Studies and Genome-Wide Association Studies

9. Statistical Analysis of Genetic Association Study Results

10. Bioinformatics for the Interpretation of Genetic Association Study Results

11. Genetic Risk Profiling and Medical Applications of Genetic Associations