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DNA methylation

basic mechanisms ; with 3 tables
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Year: 2006
Publisher: Berlin [u.a.], Springer
Series: Current topics in microbiology and immunology; 301
Media group: Serien
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Content

Inhaltsverzeichnise (Kurzversion) - Table of Contents (short version)
 
Introduction
The Almost Forgotten Fifth Nucleotide in DNA: An Introduction
 Pattern Formation
Replication and Translation of Epigenetic Information
 DNA Methyltransferases. Facts, Clues, Mysteries
 DNA Methylation in Plants
 Determinant of Promoter Activity
DNA Methylation: De novo Methylation, Long-term Promoter Silencing, Methylation Patterns in the Human Genome, and Consequences of Foreign DNA Insertion
 DNA Methyltransferases
Establishment and Maintenance of DNA Methylation Patterns in Mammals
 Molecular Enzymology of Mammalian DNA Methyltransferases
 Epigenetic Phenomena
Familial Hydratidiform Molar Pregnancy: the Germline Imprinting Defect Hypothesis
 Dual Inheritance
 Mutagenesis and Repair
Mutagenesis at Methylated CpG Sequences
 Cytosine Methylation and DNA Repair
 Subject Index.
 
Thema
methyltransferase; epigenetic information; human genome; methylation patterns; cytosine methylation; dual inheritance system; Science-Titel (SC)
 
Beschreibung
The structural and functional importance of the correct patterns of DNA methylation in all parts of a mammalian genome is, unfortunately, not well understood. The stability, inheritability, and developmental flexibility of these patterns all point to a major role that these patterns appear to play in determining structure and funtion of the genome. Up to the present time, studies on the repetitive sequences, which comprise more than 90 per cent of the DNA sequences in the human or other genomes, have been neglected.

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Details

Search for this author
Statement of Responsibility: W. Doerfler and P. Böhm (Eds.)
Year: 2006
Publisher: Berlin [u.a.], Springer
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Classification: Search for this systematic MB-10, ZB-90
Subject type: Search for this subject type Sammelwerke
ISBN: 3540291148
Description: VI, 321 S. : Ill., graph. Darst.
Series: Current topics in microbiology and immunology; 301
Tags: Mikrobiologie; Mikrobiologie allgemein; Immunbiologie; Immunology; Zellbiologie
Participating parties: Search for this character Doerfler, Walter [Hrsg.]; Böhm, Petra [Hrsg.]
Language: englisch||
Footnote: Literaturangaben
Media group: Serien