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Proteins: Concepts in Biochemistry teaches the biochemical concepts underlying protein structure, evolution, stability, folding, and enzyme kinetics, and explains how interactions in macromolecular structures determine protein function. Intended for a one-semester course in biochemistry or biophysical chemistry with a focus on proteins, this textbook emphasizes the logic underlying biophysical chemical principles.

 

Problems throughout the book encourage statistical and quantitative thinking. The text is ideal for senior undergraduates, first year graduate students, and practitioners in chemistry, biochemistry, biology, and biophysics.

Table Of Contents:

1.Statistical Thermodynamics of Biological Molecules

2.Protein Structure

3.Evolution of Protein Sequence and Structure

4.Protein Stability

5.Protein Folding

6.Binding, Allostery, and Cooperativity

7.Enzyme Kinetics

Appendix A. Calculation of the excess heat capacity curve of protein thermal denaturation

Appendix B. Calculation of the average helicity from the partition function

Appendix C. Solution of rate equations for two-state system