This book covers a wide range of subjects in applying machine learning approaches for bioinformatics projects. The book succeeds on two key unique features. First, it introduces the most widely used machine learning approaches in bioinformatics and discusses, with evaluations from real case studies, how they are used in individual bioinformatics projects. Second, it introduces state-of-the-art bioinformatics research methods. The theoretical parts and the practical parts are well integrated for readers to follow the existing procedures in individual research.
Unlike most of the bioinformatics books on the market, the content coverage is not limited to just one subject. A broad spectrum of relevant topics in bioinformatics including systematic data mining and computational systems biology researches are brought together in this book, thereby offering an efficient and convenient platform for teaching purposes.
An essential reference for both final year undergraduates and graduate students in universities, as well as a comprehensive handbook for new researchers, this book will also serve as a practical guide for software development in relevant bioinformatics projects.
Contents:
Introduction to Unsupervised Learning
Probability Density Estimation Approaches
Dimension Reduction
Cluster Analysis
Self-Organizing Map
Introduction to Supervised Learning
Linear/Quadratic Discriminant Analysis and K-Nearest Neighbour
Classification and Regression Trees, Random Forest Algorithm
Multi-Layer Perceptron
Basis Function Approach and Vector Machines
Hidden Markov Model
Feature Selection
Feature Extraction (Biological Data Coding)
Sequence/Structural Bioinformatics Foundation — Peptide Classification
Gene Network — Causal Network and Bayesian Networks
S-Systems
Future Directions
Statement of Responsibility:
Zheng Rong Yang
Year:
2010
Publisher:
New Jersey, World Scientific
Articles:
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Classification:
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MA-20, BI-50
ISBN:
9789814287302
ISBN (2nd):
981428730X
Description:
XIV, 322 S. : graph. Darst.
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Language:
englisch||
Footnote:
Literaturverz. S. 279 - 317
Media group:
Dauerleihe