Technologien und Anwendungen der "weißen" Biochemie diskutieren die Autoren dieses Bandes unter Berücksichtigung des wirtschaftlichen Potenzials jeder Methode und der Folgen für die Gesellschaft. Der eher allgemein gehaltene Text verschafft dem Neueinsteiger auch einen aufschlussreichen Einblick in viele Industriezweige.
Aus dem Inhalt
Preface
THE SCOPE AND IMPACT OF INDUSTRIAL BIOTECHNOLOGY
HISTORY OF INDUSTRIAL BIOTECHNOLOGY
Early History
The Penicillin Story
The Coming of the Cephalosporins
The Waksman Era
Strain Improvement
Semi-Synthetic Antibiotics to Combat Resistant Microbes
The Primary Metabolites
The Shift from Antibiotics to Pharmacological Agents
The Biopharmaceutical Revolution
Recombinant Hosts
Enzymes
Bioconversions
Vaccines
Systems Microbiology
INDUSTRIAL SYSTEMS BIOLOGY
Introduction
Industrial Biotechnology
Market Drivers for Industrial Biotechnology
Industrial Systems Biology
Metabolic Models
Reconstructed Metabolic Network Models
Industrial Systems Biology Case Studies
Conclusion and Future Perspectives
FERMENTATION TECHNOLOGY
Introduction
Types of Fermentations
Fermentation Process
Fermentation Medium Design
sterilization of Air and Fermentation Medium
Environmental Factors
Fermentation Kinetics
Fermentation Equipment
Recovery of Fermentation Products
Concluding Remarks
DIRECTED EVOLUTION OF INDUSTRIAL BIOCATALYSTS
Introduction
Strategies for Protein Design
Assay Systems
Examples
Conclusions
THE INDUSTRIAL PRODUCTION OF ENZYMES
Introduction
Enzyme Production
Enzyme Improvement
Large-Scale Enzyme Applications
Conclusions
APPLIED BIOCATALYSIS: AN OVERVIEW
Introduction
The Design of the Bioconversion System
Bioreactors
Rationalizing and Speeding Up the Development and Characterization of a Bioconversion Process
Concluding Remarks
NANOBIOTECHNOLOGY
Setting the Stage
Industrial Perspective
Nanotechnology in Biology and Biochemistry
Biomimicry
Materials and Products
Processes and Devices
Outlook
DOWNSTREAM PROCESSING IN INDUSTRIAL BIOTECHNOLOGY
Introduction
Separations in Industrial Biotechnology
Examples of Downstream Processing of Different Product Groups
INDUSTRIAL BIOTECHNOLOGY IN THE CHEMICAL AND PHARMACEUTICAL INDUSTRIES
Introduction
Biocatalytic Processes: Scientific and Technological Perspectives
Biocatalytic Processes: Business and Commercial Perspective
Safety, Health, and the Environmental Perspective
Outlook
INDUSTRIAL BIOTECHNOLOGY IN THE FOOD AND FEED SECTOR
Introduction
Food Applications
Food and Feed Applications
Feed Applications
INDUSTRIAL BIOTECHNOLOGY IN THE PAPER AND PULP SECTOR
Introduction
Enzymes for the Pulp and Paper Industry
Enzymes as Process Aids
Enzymes for Product Design
Biorefinery Concepts
Conclusions
BIOFUELS: PRODUCTION AND APPLICATIONS
A Renewed Interest in Biofuels
Present Conversion Pathways
Biodiesel Production from Vegetable Oils and Fats
Ethanol and ETBE Production
The Need for New Developments
Lignocellulosic Biomass Resources
Production of Ethanol from Lignocellulosic Biomass
Production of Biofuels Through the Thermochemical Pathway
Biorefineries
Biofuels and Sustainability
Conclusion
ENVIRONMENTAL AND ECONOMIC ASPECTS OF INDUSTRIAL BIOTECHNOLOGY
Introduction
Methodology
Overall Results
Conclusions
SOCIETAL ISSUES IN INDUSTRIAL BIOTECHNOLOGY
Introduction
The Impact of Industrial Biotechnology
Public Perceptions of Industrial Biotechnology
Societal Issues in Industrial Biotechnology
Conclusions and Discussions: A Joint Agenda for the Smooth Introduction of Acceptable Sustainable Industrial Biotechnology