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Proteomics of biological systems

protein phosphorylation using mass spectrometry techniques
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Author: Search for this author Ham, Bryan M.
Year: 2012
Publisher: Hoboken, NJ, Wiley
Media group: Ausleihbestand
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Branch: Hauptstelle Locations: NA-30 200 Status: available Reservations: 0 Due date: Barcode: 00259560 Floor plans: Floor plan Lending note:

Content

Phosphorylation is the addition of a phosphate (PO4) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes, causing or preventing the mechanisms of diseases such as cancer and diabetes. This book shows how to use mass spectrometry to determine whether or not a protein has been correctly modified by the addition of a phosphate group. It also provides a combination of detailed, step-by-step methodology for phosphoproteomic sample preparation, mass spectral instrumental analysis, and data interpretation approaches. Furthermore, it includes the use of bioinformatic Internet tools such as the Blast2GO gene ontology (GO) tool, used to help understand and interpret complex data collected in these studies.

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Author: Search for this author Ham, Bryan M.
Statement of Responsibility: Bryan M. Ham
Year: 2012
Publisher: Hoboken, NJ, Wiley
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Classification: Search for this systematic NA-30, SP-20, GE-40
Subject type: Search for this subject type Monographien
ISBN: 9781118028964
ISBN (2nd): 1-118-02896-1
Description: XXIII, 350 S. : Ill., graph. Darst.
Tags: Proteine; Massenspektroskopie; Genetik Methoden; Proteomics; Methodology; LC; Phosphorylation; Research; Phosphoproteins; Synthesis; Mass spectrometry; Biological systems
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Language: englisch||
Footnote: Literaturangaben
Media group: Ausleihbestand