Over the past twenty-five years, the number of patients with compromised immune systems has grown astronomically. High-risk patients such as these require a unique set of healthcare solutions that take into consideration everything from the etiology and degree of immune suppression to the individual patient’s nutritional status. This comprehensive volume, assembled by a group of distinguished authors, examines a wide range of approaches and challenges to infectious disease diagnostics for immunocompromised patients.
Divided into four sections, the book takes a multifaceted approach to the detection and characterization of infections encountered in this high-risk patient group. The first section provides a broad explanation of the causes of immune suppression, the populations at risk for infections, and the various kinds of infections. The next section addresses crucial laboratory diagnostic methods for individual pathogens, while the third section takes a more systematic perspective on the affected organs in immunocompromised patients. The volume concludes with a discussion of future trends in the field. The material is clearly summarized in practical, user-friendly procedures that can be applied to everyday patient care challenges.
Table of Contents
I. Hosts and Infections
1. Overview of Infections in the Immunocompromised Host, Lesia K. Dropulic and Howard M. Lederman
II. Laboratory Diagnosis: Specific Etiologic Agents
2. Human Immunodeficiency Virus, Yun F. (Wayne) Wang, Molly Eaton, Audrey N. Schuetz, and Steven Nesheim
3. Cytomegalovirus, Cari R. Sloma, Thomas E. Grys, and Raymund R. Razonable
4. Epstein-Barr Virus and Human Herpesvirus 8, David T. Rowe, Frank J. Jenkins, and Heather R. Hensler
5. Herpes Simplex Virus, Varicella-Zoster Virus, Human Herpesvirus 6, and Human Herpesvirus 7, Paula A. Revell, James H. Clark, III and Beverly B. Rogers
6. Adenovirus, Michael G. Ison and Randall T. Hayden
7. RNA Respiratory Viruses, Michael G. Ison and Eric S. Rosenberg
8. Enteroviruses, James J. Dunn
9. Parvovirus, Marie Louise Landry
10. Filamentous Fungi, Gary W. Procop, Randall T. Hayden, and Glenn D. Roberts
11. Yeasts, Justin A. Bishop and William G. Merz
12. Mycobacteria, Nancy G. Warren and Gail L. Woods
13. Aerobic Actinomycetes, Michael A. Saubolle
14. Parasites, Lynne S. Garcia
III. Laboratory Diagnosis: an Organ Systems Approach
15. Lower Respiratory Tract Infections, Karen C. Carroll
16. Genitourinary Tract Infections, Barbara L. Haller
17. Gastrointestinal Infections, Irving Nachamkin
18. Central Nervous System Infections, Igen Hongo, Karen C. Bloch, and Yi-Wei Tang
19. Bloodstream Infections, Cathy A. Petti, Hafsa Hassan, and L. Barth Reller
20. Soft Tissue and Prosthetic Device Infections, Xiang Y. Han
21. Hospital-Associated Infections, Fann Wu, Susan Whittier, and Phyllis Della-Latta
IV. Future Trends
22. Future Trends in Diagnosis of Infections in the Immunocompromised Population, Donna M. Wolk and Elizabeth M. Marlowe