Branch	Locations	Status	Reservations	Due date	Barcode	Floor plan	Lending note
Branch: Hauptstelle	Locations: BC-40 63	Status: available	Reservations: 0	Due date:	Barcode: 00186449	Floor plans: Floor plan	Lending note:

About this book

 

The peroxiredoxins represent an important emerging family of sulfhydryl-linked antioxidant proteins, apparently ubiquitously present in all known organisms. The antioxidant function of the peroxiredoxins complements that of other enzymic and non-enzymic systems within the cell. In addition, there is increasing evidence that the peroxiredoxins play a role in cell signaling, by controlling and/or sensing hydrogen peroxide and peroxynitrite levels.

 

This book contains a broad survey on the peroxiredoxins. It involves almost all groups that contributed significant insights into the emerging field. Coverage discusses the diverse biological roles of the new protein family in the context of other antioxidant systems like those based on heme or selenium catalysis. In addition, the book highlights related future perspectives, which range from antimicrobial therapy up to the understanding of human development and carcinogenesis. It will be of interest to researchers who want to understand how micro-organisms, plants and animals cope with oxidative stress and how such stress is recognized and linked to adaptive responses via redox regulation of cellular processes.

 

 

Table of contents

 

Contributing Authors

Preface

 

Chapter 1. Introduction: History of the Peroxiredoxins and Topical Perspectives

Leopold Flohé and J. Robin Harris

 

Chapter 2. Evolution of the Peroxiredoxins (Taxonomy/Homology/Characterization)

Bernard Knoops, Eléonore Loumaye and Valérie Van der Eecken

 

Chapter 3. Structural Survey of the Peroxiredoxins

P. Andrew Karplus and Andrea Hall

 

Chapter 4. The Catalytic Mechanism of Peroxiredoxins

Leslie B. Poole

 

Chapter 5. Kinetics of Peroxiredoxins and their Role in the Decomposition of Peroxynitrite

Madia Trujillo, Gerardo Ferrer-Sueta, Leonor Thomson, Leopold Flohé and Rafael Radi

 

Chapter 6. The Peroxiredoxin Repair Proteins

Thomas J. Jönsson and W. Todd Lowther

 

Chapter 7. Peroxiredoxins in Bacterial Antioxidant Defense

James M. Dubbs and Skorn Mongkolsuk

 

Chapter 8. The NADH oxidase-Prx system in Amphibacillus xylanus

Youichi Niimura

 

Chapter 9. Peroxiredoxin Systems in Mycobacteria

Timo Jaeger

 

Chapter 10. Peroxiredoxin systems of protozoal parasites

Marcel Deponte, Stefan Rahlfs and Katja Becker

 

Chapter 11. The Trypanaothione System

Luise R. Krauth-Siegel, Marcelo A. Comini and Tanja Schlecker

 

Chapter 12. Functions of Typical 2-Cys Peroxiredoxins in Yeast

Brian A. Morgan and Elizabeth A. Veal

 

Chapter 13. The Dual Function of Plant Peroxiredoxins in Antioxidant Defence and Redox Signaling

Karl-Josef Dietz

 

Chapter 14. Mitochondrial Peroxiredoxins: Structure and Function

Zhenbo Cao, J. Gordon Lindsay and Neil W. Isaacs

 

Chapter 15. Peroxiredoxins in the Lung with Emphasis on Peroxiredoxin VI

Bruno Schremmer, Yefim Manevich, Sheldon I. Feinstein, and Aron B. Fisher.

 

Chapter 16. Peroxiredoxins in Gametogenesis and Embryo Development

Isabelle Donnay and Bernard Knoops

 

Chapter 17. Peroxiredoxins in the Central Nervous System

Fumiyuki Hattori and Shinzo Oikawa

 

Chapter 18. Stress-induced Peroxiredoxins

Tetsuro Ishii and Toru Yanagawa

 

Index