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Cytochrome P450 2E1

its role in disease and drug metabolism
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Year: 2013
Publisher: Dordrecht, Springer
Series: Subcellular biochemistry; 67
Media group: Ausleihbestand
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Branch: Hauptstelle Locations: BC-40 68 Status: available Reservations: 0 Due date: Barcode: 00264466 Floor plans: Floor plan Lending note:

Content

The book deals with various clinical aspects of cytochrome P450 2E1 (CYP2E1), which is a potent source for oxidative stress. Oxidative stress is critical for pathogenesis of diseases and CYP2E1 is a major contributor for oxidative stress. Several clinical disorders are associated with changes in regulation of CYP2E1 and the consequent abnormalities, which include alcoholic liver disease, alcoholic pancreatitis, carcinogenesis, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, obesity, hepatitis C virus infection, reproductive organ toxicity, hepatocellular and cholestatic liver cirrhosis, inhibition of bone repair, cross-tolerance in smokers and people treated with nicotine, disorders of the central nervous system, changes in metabolism of protoxicants in the circulatory system and susceptibility to human papillomavirus infection. Hence, CYP2E1 emerges as a new and potent player in aggravating injury and furthering disease complications.

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Statement of Responsibility: Aparajita Dey, editor
Year: 2013
Publisher: Dordrecht, Springer
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Classification: Search for this systematic BC-40, BC-50, ME-30, ME-10
Subject type: Search for this subject type Monographien
ISBN: 978-9-400-75880-3
ISBN (2nd): 9-400-75880-4
Description: XVI, 256 S. : Ill., graph. Darst.
Series: Subcellular biochemistry; 67
Tags: Medizin allgemein; Pharmazie; Enzymologie; Stoffwechselwege
Participating parties: Search for this character Dey, Aparajita [Hrsg.]
Language: Englisch
Footnote: Literaturangaben
Media group: Ausleihbestand