Written by a team of authors from academia and several large pharma companies, this first book on the topic systematically surveys drug development efforts based on chemokine signaling for HIV/AIDS, cancer, neural and autoimmune disorders.
Aus dem Inhalt
FUNDAMENTALS OF CHEMOKINES AND CHEMOKINE RECEPTORS
Structural Aspects of Chemokines, and their Interactionss with Receptors and GAGs
Structural Insights for Homology Modeling of Chemokine Receptors
Signaling Events Involved in Chemokine-Directed T Lymphocyte Migration
The Atypical Chemokine Receptors
Targeting Chemokine Receptor Dimers: Are there Two (or More) to Tango?
CHEMOKINE RECEPTORS IN DISEASE
Chemokine Receptors in Inlammatory Diseases
Chemokines and their Receptors in Central Nervous System Disease
Chemokines and Cancer Metastasis
Constitutively Active Viral Chemokine Receptors: Tools for Immune Subversion and Pathogenesis
TARGETING CHEMOKINE RECEPTORS
CCR5 Antagonists in HIV
CXCR4 as therapeutic target
Low-Molecular Weight CXCR2 Antagonists as Promising Therapeutics
Therapeutic Targeting of the CXCR3 Receptors
Targeting CCR1
Targeting CCR3
Chemokine-Binding Proteins as Therapeutics
Search for this author
Statement of Responsibility:
edited by Martine J. Smit, Sergio A. Lira, and Rob Leurs
Year:
2011
Publisher:
Weinheim, Wiley-VCH
Articles:
Go to this article
opens in new tab
ISBN:
9783527321186
ISBN (2nd):
3-527-32118-7
Description:
XXIV, 384 S. : Ill., graph. Darst.
Language:
englisch||
Footnote:
Literaturangaben
Media group:
Ausleihbestand