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Volume 2.; Volume 2

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Year: 2010
Volume: Volume 2.
Series: Current topics in microbiology and immunology; Volume 347
Media group: Serien
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Branch: Hauptstelle Locations: Serie Status: available Reservations: 0 Due date: Barcode: 00229954 Floor plans: Floor plan Lending note:

Content

Contents of sister volume 2: PI3K - From the bench to the clinic and back.- Oncogenetic mutations of PIK3CA in human cancers.- Structural effects of oncogenic PI3Kalpha mutations.- Comparing the roles of the p110alpha and p110beta isoforms of PI3K in signaling and cancer.- Phophatidylinositol 3-kinase (PI3K): the oncoprotein.- AKT Signaling in Physiology and Disease.- Faithfull modeling of PTEN loss driven diseases in the mouse.- PI3K as a target for therapy in haematological malignancies.- Clinical Development of Phosphatidylinositol-3 Kinase Pathway Inhibitors.- From the bench to the bed side: PI3K pathway inhibitors in clinical development.- New Inhibitors of the PI3K-Akt-mTOR Pathway: Insights into mTOR Signaling From a New Generation of Tor Kinase Domain Inhibitors (TORKinibs).- Small molecule inhibitors of the PI3-kinase family.- Targeting the RTK-PI3K-mTOR axis in malignant glioma: overcoming resistance.- Subject index

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Year: 2010
Volume: Volume 2.
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ISBN: 9783642148156
ISBN (2nd): 3-642-14815-8
Description: X, 301 S. : Ill., graph. Darst.
Series: Current topics in microbiology and immunology; Volume 347
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Language: englisch||
Media group: Serien