Table of Contents
SECTION I Biofilms: Background, Significance, and Roles of Catheters and Indwelling Devices
Microbial Biofilms; Xiuping Jiang and John L. Pace
Economic Impact of Biofilms on Treatment Costs; John G. Thomas, Isaiah Litton, and Harald Rinde
Biofilm-Related Indwelling Medical Device Infections; Matthew K. Schinabeck and Mahmoud A. Ghannoum
Medical Device Composition and Biological Secretion Influences on Biofilm Formation; Sean P. Gorman and David S. Jones
SECTION II Biofilm-Forming Pathogens
Role of Biofilms in Infections Caused by Escherichia coli; Grégory Jubelin, Corinne Dorel, and Philippe Lejeune
Staphylococcus aureus Biofilms; Julie M. Higashi and Paul M. Sullam
Coagulase-Negative Staphylococci; Dietrich Mack, Matthias A. Horstkotte, Holger Rohde, and Johannes K.-M. Knobloch
Pseudomonas aeruginosa Biofilm Infections in Cystic Fibrosis; Andrea Smiley and Daniel J. Hassett Candida; Stephen Hawser and Khalid Islam
SECTION III Emerging Issues, Assays, and Models
Current Perspectives on the Regulation of the ica Operon and Biofilm Formation in Staphylococcus epidermidis; Paul D. Fey and Luke D. Handke
Cell-to-Cell Communication in Bacteria; Kenneth D. Tucker and Luciano Passador
Persisters: Specialized Cells Responsible for Biofilm Tolerance to Antimicrobial Agents; Kim Lewis, Amy L. Spoering, Niilo Kaldalu, Iris Keren, and Devang Shah
Minimal Biofilm Eradication Concentration (MBEC) Assay: Susceptibility Testing for Biofilms; Howard Ceri, Merle E. Olson, Douglas W. Morck, and Douglas G. Storey
Environmental Cues Regulate Virulence and Biofilm Formation; John L. Pace and Steven M. Frey
In Vivo Models for the Study of Biomaterial-Associated Infection by Biofilm-Forming Staphylococci; Luke D. Handke and Mark E. Rupp
Host Response to Biofilms; Susan Meier-Davis
SECTION IV Overview of Antiinfective Agents and Clinical Therapy
Pharmacodynamics and the Treatment of IMD-Related Infections; Roger Finch and Sarah Gander
Protein Synthesis Inhibitors, Fluoroquinolones, and Rifampin for Biofilm Infections; Steven L. Barriere
o-Lactams for the Treatment of Biofilm-Associated Infections; Ingrid L. Dodge, Karen Joy Shaw, and Karen Bush
Glycopeptide Antibacterials and the Treatment of Biofilm-Related Infections; John L. Pace, Roasaire Verna, and Jan Verhoef
Antibiotic Resistance in Biofilms; Nafsika H. Georgopapadakou
Treatment Protocols for Infections of Vascular Catheters; Russell E. Lewis and Issam I. Raad
Treatment Protocols for Bacterial Endocarditis and Infection of Electrophysiologic Cardiac Devices; Martin E. Stryjewski and G. Ralph Corey
Treatment Protocol of Infections of Orthopedic Devices; Vera Antonios, Elie Berbari, and Douglas Osmon
Index . . . . . . . . . .