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Inflammasome signaling and bacterial infections

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Year: [2016]
Publisher: Cham [u.a.], Springer
Series: Current topics in microbiology and immunology; 397
Media group: Serien
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Branch: Hauptstelle Locations: Serie Status: available Reservations: 0 Due date: Barcode: 00297615 Floor plans: Floor plan Lending note:

Content

This volume details our current understanding of the architecture and signaling capabilities of known canonical and non-canonical inflammasome complexes and highlights their action, in particular in response to infection with important bacterial model organisms and the corresponding disease pathologies. The first chapters review new insights into the assembly and structures of inflammasome components and emphasize general strategies of up- and downstream signaling events. In addition, the authors specifically discuss the composition and activity of inflammasomes during infection with various gut pathogens (Salmonella, Shigella, Yersinia, Listeria and Helicobacter), respiratory pathogens (Mycobacterium, Legionella, Burkholderia and Streptococcus) as well as skin and soft tissue pathogens (Francisella and Staphylococcus). The discoveries presented provide a better understanding of the cellular and molecular biology of inflammasomes, which will pinpoint important new therapeutic targets for the treatment and prevention of multiple infectious diseases in the future. It is a valuable resource for students, scientists and clinicians, providing up-to-date information on this emerging research topic.
 

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Details

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Statement of Responsibility: Steffen Backert, editor. Responsible series editor Klaus Aktories
Year: [2016]
Publisher: Cham [u.a.], Springer
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Classification: Search for this systematic MB-40, ZB-90
Subject type: Search for this subject type Sammelwerk
ISBN: 978-3-319-41170-5
ISBN (2nd): 3-319-41170-5
Description: xi, 282 Seiten : Illustrationen, Grafiken
Series: Current topics in microbiology and immunology; 397
Tags: Medizinische Mikrobiologie; Immunbiologie
Participating parties: Search for this character Backert, Steffen [Herausgeber]; Aktories, Klaus [Herausgeber]
Language: Englisch
Media group: Serien