Branch	Locations	Status	Reservations	Due date	Barcode	Floor plan	Lending note
Branch: Hauptstelle	Locations: NA-10 28	Status: available	Reservations: 0	Due date:	Barcode: 00230324	Floor plans: Floor plan	Lending note:

Bioactive natural products are proving to be a rich source of novel therapeutics to both protect against and combat diseases, as well as serve as lead compounds in crop protection. Following the successful format of the first edition, this volume brings together collective research from many new contributors and emphasizes the rationale behind the successful detection, isolation, and structure determination of specific compounds. The text encompasses a diverse range of techniques that can be applied to terrestrial and aquatic sources. It also allows you to understand how source material can be selected to enhance your opportunity to discover and utilize novel bioactive natural products.

New to the Second Edition—

 

· Advances in the application of NMR spectroscopy and mass spectrometry, bioactive chemical detection and extraction, dereplication, and novel bioassay development

 

· New case studies and illustrations that demonstrate the practical applications of specific techniques

 

· A group of new contributors presenting research from their own laboratories that emphasize both the philosophy and rationale behind detection, isolation, and structural determination

 

Following an overview of natural product chemistry techniques and approaches, many new chapters discuss selection of source material, quantitative NMR, high speed counter-current chromatography, dereplication of extracts, and methods to determine the stereochemistry of bioactive natural products. Examinations of new technologies including LC-NMR, biosensors, and biofingerprinting accompany discussions on the search for specific activities in anticancer and antimalarial applications, seed germination stimulation, and mammalian toxicity.

 

With the participation from active researchers, this definitive work supplies a vital extension and an enduring contribution to the science and art of bioactive natural product detection, isolation, and structural determination.

Table of contents:

Introduction and Overview

Detection and Isolation of Bioactive Natural Products

Nuclear Magnetic Resonance Spectroscopy: Strategies for Structure Determination

Quantitative NMR of Bioactive Natural Products

Development and Application of LC-NMR Techniques to the Identification of Bioactive Natural Products

Determination of the Absolute Configuration of Bioactive Natural Products using Exciton Chirality Circular Dichroism

Separation of Enantiomeric Mixtures of Alkaloids and their Biological Evaluation

UV Dereplication of Natural Products Extracts

Liquid Chromatography-Mass Spectrometry in Natural Product Research

Application of High-Speed Counter-Current Chromatography to the Isolation of Bioactive Natural Products

Biosensing Approach in Natural Products Research

Anticancer Drug Discovery and Development from Natural Products

Sourcing Natural Products from Endophytic Microbes

Isolation of Bioactive Natural Products from Myxobacteria

Naturally-occurring Glycosidase Inhibitors

Bioassay-Directed Isolation and Identification of Anti-aflatoxigenic

Constituents of Walnuts

Bioactive Peptides in Hen Eggs

Biological Fingerprinting Analysis: Strategy for Screening of Bioactive Compounds in Traditional Chinese Medicines

Antimalarial Compounds from Traditionally-used Medicinal Plants

Germination Stimulant in Smoke: Isolation and Identification

Plant-associated Toxins: Bioactivity-guided Isolation, Elisa and LCMS Detection