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About this book

 

The convergence of life sciences and micro/nanotechnologies is one of the fastest growing modern R and D areas with an enormous potential societal impact. Microfluidics or Lab-on-Chip (LOC) devices, also dubbed BioMEMS, are a fascinating example of this combination of two scientific areas.

 

This book, which is the first volume entirely dedicated to microfabricated cell-based systems, will provide readers with a quick introduction to the field as well as with a variety of specific examples of such Lab-on-Chip systems for cellomics applications. It will give investigators inspiration for innovative research topics, whereas end users will be surprised about the wide variety of new and exciting applications.

 

Table of contents

 

1: Microfluidic devices for cellomics; H. Andersson and A. van den Berg

 

2: Pretreatment of biological samples for microchip analysis; J. Ferrance, J. Landers

 

3: Liposomes as cellular model systems; L Locascio, W. Vreeland, A. Jahn, and M. Gaitan

 

4: A versatile chip-based tool for the controlled manipulation of microparticles in biology using high frequency electromagnetic fields; C. Duschl, P. Geggier, M. Jäger, M. Stelzle, T. Müller, T. Schnelle, G. Fuhr

 

5: Microelectroporation in cellomics; B. Rubinsky

 

6: Patch clamp microsystems; T. Lehnert and M. Gijs

 

7: Using lab-on-a-chip technologies to understand cellular mechanotransduction; D. Pirone and C. Chen

 

8: Analysis of apoptosis on chip; F. Wolbers, C. Haanen, H. Andersson, A. van den Berg and I. Vermes

 

9: On chip single cell cultivation systems; K. Yasuda

 

10: Human embryonic stem cells and microfluidics; V. Abhyankar and D. Beebe

 

11: Cellular and subcellular analysis on chip; H. Lu, K. Jensen

 

12: Microfluidic cell culture devices; Y. Sakai, E. Leclerc , and T. Fujii

 

13: Micromachined bioreactor for in vitro cell self-assembly and 3D tissue formation; K. Domansky, A. Sivaraman and L. Griffith