Themen dieses Bandes sind die molekularen Mechanismen der Tumor-Angiogenese, die Suche nach einschlägigen Targets für die Wirkstoffforschung und die Entwicklung von Kombinationstherapien mit bereits existierenden Ansätzen. Die ideale Informationsquelle für Studenten, Ärzte und Forscher in der Pharmaindustrie!
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INTRODUCTION
Overview on Tumor Angiogenesis (Donati, Lorenzet)
MECHANISMS OF ANGIOGENESIS AND LYMPHANGIOGENESIS
Molecular Mechanisms of Angiogenesis (Dudley, Claesson-Welsh)
Pro-angiogenic Factors (Ribatti)
The Role of Accessory Cells in Tumor Angiogenesis (Takakura)
Comparison between Developmental and Tumor Angiogenesis (Bikfalvi)
Tumor Lymphangiogenesis (Ramu, Hong)
SIGNAL TRANSDUCTION AND ANGIOGENESIS
Integrin Involvement in Angiogenesis (Akalu, Contois, Brooks)
Signaling Pathways in Tumor Angiogenesis (Abrahams, Daly, Eichten, Li, Noguera-Troise, Thurston)
THERAPEUTIC APPROACHES AND ANGIOGENESIS
Development of an Integrin Targeted Anti-Angiogenic Agent (Swenson, Minea, Markland)
Anti-VEGF Approaches and Newer Antiangiogenic Agents (including combrestatins) which are already in Clinical (Libutti)
Combination of Antiagiogenic Therapy with Other Anticancer Therapies (Gasparini)
Tumor specificity of anti-angiogenic agents (Rixe, Kelly, Giaccone)
IMAGING AND BIOMARKERS IN ANGIOGENESIS
In vivo imaging of tumor angiogenesis (Turkbey, Ravizzini, Choyke)
Identifying Biomarkers to Establish Drug Efficacy (Platero)
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Statement of Responsibility:
edited by Francis S. Markland, Stephen Swenson, and Radu Minea
Year:
2010
Publisher:
Weinheim, Wiley-Blackwell
Articles:
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Standort A002
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Classification:
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ZB-100
ISBN:
9783527320912
ISBN (2nd):
3-527-32091-1
Description:
XXII, 329 S. : Ill., graph. Darst.
Language:
englisch||
Footnote:
Literaturangaben
Media group:
Ausleihbestand