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Bioanalytical Chemistry for Life and Health Sciences: Principles and Applications is a single core textbook, with supplementary learning materials, which provides a novel teaching and learning resource for tutors and students of first year undergraduate chemistry. The book describes basic principles, terminology, and core technologies, which include modern experimental techniques and equipment used to analyse important biomolecules in diagnostic, industrial, and research laboratory settings. It also provides an introduction to advanced technologies used in the emerging fields of genomics, peptidomics/proteomics, and metabolomics.

 

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Contents

 

Preface

 

1 Introduction to biomolecules

 

2 Analysis and quantification of biomolecules

 

3 Transition metals in health and disease

 

4 Ions, electrodes and biosensors

 

5 Applications of spectroscopy

 

6 Centrifugation and separation

 

7 Chromatography of biomolecules

 

8 Principles and applications of electrophoresis

 

9 Applications of mass spectrometry

 

10 Immunochemical techniques and biological tracers

 

11 Bioanalysis by magnetic resonance technologies: NMR and MRI

 

12 Bioanalytical approaches from diagnostic, research and pharmaceutical perspectives

 

13 Self-Assessment

 

Appendix 1: International system of units (SI) and common prefixes

 

Appendix 2: The periodic table of the elements

 

Appendix 3: Common solvents and biological buffers

 

Appendix 4: Answers to self-assessment questions

 

Index