Table of Contents
SECTION I Free Radicals, Lifestyle-Related
Diseases, and Their Protection
Redox Regulation as an Underlying Factor in Health and Disease: Junji Yodoi, Norihiko Kondo, Yasuyuki Ishii, Junko Sakakuara, and Hajime Nakamura
Diet and Lifestyle in Cancer Prevention: David Heber
The Gene Regulatory Mechanism of Thioredoxin and Thioredoxin Binding Protein-2/VDUP1 in Cancer Prevention: Hiroshi Masutani, Yumiko Nishinaka, Yong-Chul Kim, and Junji Yodoi
Coenzyme Q10, Free Radicals, and Heart Disease: Yorihiro Yamamoto
Wine, Alcohol, and a Healthy Heart: Dipak K. Das and Nilanjana Maulik
Diabetes Treatment by Alpha-Lipoic Acid: Modulation of Glucose Uptake and Adipocyte Differentiation: An-Sik Chung, Kyung-Joo Cho, and Lester Packer
The Mechanism of Immune Suppression by GIF and Cysteinylated MIF at Cys-60: Yasuyuki Ishii, Aoi Son, Norihiko Kondo, Junko Sakakura-Nishiyama, Yoshiyuki Matsuo, and Junji Yodoi
Role of Free Radicals in Cellular Damage and Its Modification by Antioxidants: Implications for Cancer Therapy: K.P. Mishra
Free Radical, Cigarette Smoke, and Health Scavenging Effects of Pycnogenol® on Free Radicals Generated from Cigarette Smoke and Its Detoxification Effects: Baolu Zhao
SECTION II
Free Radicals, Brain Diseases, and Their Protection
Free Radical Scavengers and Neuroprotection: Midori Hiramatsu
Oxidative Adaptation in Aging and Alzheimer's Disease: The Roles of Amyloid and Tau: Hyoung-gon Lee and Xiongwei Zhu, Kelly L. Drew, James A. Joseph, Akihiko Nunomura, Keisuke Hirai, Atsushi Takeda, George Perry, and Mark A. Smith
Coenzyme Q10 Stabilizes Mitochondria in Parkinson's Disease: Manuchair Ebadi, Sawitri Wanpen, Shaik Shavali, and Sushil Sharma
The In Vitro and In Vivo Molecular Mechanisms of Neuroprotection by the Major Green Tea Polyphenol, (-)-Epigallocatechin-3-gallate, with Special Reference to Parkinson's Disease: Orly Weinreb, Silvia Mandel, Tamar Amit, and Moussa B.H. Youdim
Kainic-Acid-Induced Neurotoxicity: Involvement of Free Radicals: Akitane Mori, Toshiki Masumizu, Isao Yokoi, and Lester Packer
Prevention of Cerebral Oxidative Stress Using Traditional Chinese Medicines: A Model of Antioxidant-Based Composite Formula: Tetsuya Konishi
Analysis of the Oxidative Stress State in Disease Development of Senescence-Accelerated Mouse: Seiichi Matsugo, Fumihiko Yasui, and Kazuo Sasaki
SECTION III Nutraceuticals, Functional Foods, Micronutrients, and Pharmacological Interventions
The Antioxidant Evolution: From Free Radical Scavenging to the Antioxidant Network and Gene Regulation by Flavonoids and Bioflavonoid-Rich Extracts from Pine Bark and Gingko Biloba Leaf : Lester Packer
New Horizons in Vitamin E Research: Etsuo Niki
Gastrointestinal Inflammatory Diseases: Role of Chemokine: Toshikazu Yoshikawa and Yuji Naito
Oxidative Stress Involvement in Diabetic Nephropathy and Its Prevention by Astaxanthin: Yuji Naito, Kazuhiko Uchiyama, and Toshikazu Yoshikawa
Preventive and Therapeutic Effects of Plant Polyphenols through Suppression of Nuclear Factor-Kappa B: Navindra P. Seeram, Haruyo Ichikawa, Shishir Shishodia, and Bharat B. Aggarwal
Ascorbic Acid and Oxidative Damage to DNA: Interrelationships and Possible Relevance to Lifestyle-Related Diseases: I.F.F. Benzie, C.K. Chan, S.W. Choi, and Y.T. Szeto
The Role of Lipid Peroxidation in Chromosomal DNA Fragmentation Associated with Cell Death Induced by Glutathione Depletion: Yoshihiro Higuchi, Hideji Tanii, Yuji Mizukami, and Tanihiro Yoshimoto
Antioxidant Properties of Select Indian Medicinal Plants in Relation to Their Therapeutic Effects: J.C. Tilak, S. Adhikari, B. Lakshmi, K.K. Janardhanan, and T.P.A. Devasagayam
Antioxidant Activity of Tendai-Uyaku Extract: Tosiki Masumizu, Takao Kaneyuki, and Akitane Mori
Detection of Active Oxygen Species in the Decomposition Process of Peroxovanadium (V) Complexes: Seiichi Matsugo, Shingo Hayakawa, Chie Mihara, and Kan Kanamori
Structural Determination and Antioxidative Activity of Oxidation Products of Flavonoids with Reaction Oxygen Species: Yuko Hirose, Toshiyuki Washizu, Yuzo Uchida, and Seiichi Matsugo
Reactivity of Anthocyanin toward Reactive Oxygen and Reactive Nitrogen Species: Takashi Ichiyanagi, Yoshihiko Hatano, Seiichi Matsugo, and Tetsuya Konishi