Virology is one of the most dynamic areas of clinical medicine. The new second edition of this essential reference has been extensively revised and updated to incorporate the latest developments and relevant citations. Covering pathogenesis, epidemiology, diagnosis, treatment, and prevention, Clinical Virology informs scientists and health care professionals about all the medically relevant aspects of this rapidly evolving field.
Clinical Virology is divided into two major sections. The first section addresses infections and syndromes related to particular organ systems, as well as the fundamentals of modern medical virology, including immune responses and vaccinology, diagnostics, antivirals, and gene therapy. The second section provides agent-specific chapters that detail the virology, epidemiology, pathogenesis, clinical manifestations, laboratory diagnosis, and prevention and treatment of important human viral pathogens.
Offering comprehensive, original coverage of the viruses that cause human disease, this is the definitive reference work on clinical virology.
Key Features
* Common templates for the syndrome-specific and separately for the agent-specific chapters allow the reader to readily access material
* New chapters on TTV and zoonotic paramyxoviruses
* Covers molecular biology, pathogenesis, immunity, clinical manifestations, treatment, and prevention
* Contributors are all internationally recognized experts actively involved in their fields
1 Introduction, Douglas D. Richman, Richard J. Whitley, and Frederick G. Hayden
SECTION I: VIRAL SYNDROMES AND GENERAL PRINCIPLES
2. Respiratory Infections John J. Treanor
3. Viral Central Nervous System Infections, Kevin A. Cassady and Richard J. Whitley
4. Viral Gastroenteritis, Paul E. Kilgore and Roger I. Glass
5. Viral Hepatitis, Kevin M. Korenblat and Jules L. Dienstag
6. Infections in Organ Transplant Recipients, John A. Zaia
7. Viral Diseases of the Heart and Muscle, Catherine Diamond and Jeremiah G. Tilles
8. Viral Infections Involving the Skin, Melody Vander Straten, Daniel Carrasco, and Stephen K. Tyring
9. Viral Hemorrhagic Fevers: a Comparative Appraisal, Karl M. Johnson
10. Viral Disease of the Eye, Garry Shuttleworth, Carolyn Shimeld, and David Easty
11. Antiviral Agents, Roger T. Inouye, Lori A. Panther, C. Mhorag Hay, and Scott M. Hammer
12. Diagnosis of Viral Infections, Steven Specter, Richard L. Hodinka, Danny L. Wiedbrauk, and Stephen A. Young
13. Immune Responses to Viruses, Jonathan W. Yewdell and Jack R. Bennink
14. Immunization against Viral Diseases, Raphael Dolin
15. Gene Therapy and Viruses, Donald B. Kohn, Barrie Carter, and Joseph C. Glorioso
16. Chronic Fatigue Syndrome, Andrew R. Lloyd, Ian Hickie, and Phillip K. Peterson
SECTION II: THE AGENTS
Part A: DNA Viruses
17. Poxviruses, Frank Fenner
18. Herpes Simplex Viruses, Richard J. Whitley and Bernard Roizman
19. Cercopithecine Herpesvirus (B Virus), Richard J. Whitley and Julia Hilliard
20. Varicella-Zoster Virus, Anne A. Gershon and Saul J. Silverstein
21. Cytomegalovirus, Paul David Griffiths and Vincent Clive Emery
22. Human Herpesvirus 6 and Human Herpesvirus 7, Koichi Yamanishi
23. Epstein-Barr Virus, Brian L. Beaulieu and John L. Sullivan
24. Kaposi's Sarcoma-Associated Herpesvirus, Patrick S. Moore and Yuan Chang
25. Adenoviruses, Olli Ruuskanen, Olli Meurman, and Göran Akusjärvi
26. Polyomaviruses, John E. Greenlee and Frank J. O'Neill
27. Papillomavirus, William Bonnez
28. Human Parvovirus B19, Larry J. Anderson
29. TT Virus and Related Human Circoviruses, Peter Simmonds
30. Hepatitis B Virus, Jean-Pierre Zarski, Don Ganem, and Teresa L. Wright
Part B: RNA Viruses
31. Human Lymphotropic Viruses: HTLV-1 AND HTLV-2, William A. Blattner
32. Human Immunodeficiency Virus, John C. Guatelli, Robert F. Siliciano, Daniel R. Kuritzkes, and Douglas D. Richman
33. Colorado Tick Fever Virus and Other Arthropod-Borne Reoviridae, Joseph K. Wong
34. Rotaviruses, Manuel A. Franco and Harry B. Greenberg
35. Respiratory Syncytial Virus and Parainfluenza Viruses, Pedro A. Piedra, Janet A. Englund, and W. Paul Glezen
36. Measles Virus, Michael N. Oxman
37. Mumps Virus, John W. Gnann, Jr.
38. Zoonotic Paramyxoviruses, William J. Bellini, Paul A. Rota, and Umesh Parashar
39. Rhabdoviruses, Thomas P. Bleck and Charles E. Rupprecht
40. Filoviridae, Mike Bray
41. Influenza Virus, Frederick G. Hayden and Peter Palese
42. Bunyaviridae: Bunyaviruses, Phleboviruses, Nairoviruses, and Hantaviruses, Gregory J. Mertz
43. Arenaviruses, C. J. Peters
44. Enteroviruses, Harley A. Rotbart
45. Rhinovirus, Jack M. Gwaltney, Jr., and Beverly A. Heinz
46. Hepatitis A Virus, Stephen M. Feinstone and Ian D. Gust
47. Norwalk Virus and Related Caliciviruses Causing Gastroenteritis, Robert L. Atmar and Mary K. Estes
48. Hepatitis E Virus, David A. Anderson and Iswar L. Shrestha
49. Astrovirus, Suzanne M. Matsui
50. Coronaviruses, Kenneth McIntosh
51. Flaviviruses, Thomas P. Monath and Theodore F. Tsai
52. Hepatitis C Virus, Laurence Garnier, Geneviève Inchauspé, and Christian Trépo
53. Alphaviruses, Theodore F. Tsai, Scott C. Weaver, and Thomas P. Monath
54. Rubella Virus, David W. Kimberlin
Part C: Subviral Agents
55. Hepatitis D Virus, Antonina Smedile, Alessia Ciancio, and Mario Rizzetto
56. Transmissible Spongiform Encephalopathies (Prion Protein Diseases), Bruce Chesebro and Byron Caughey