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Next generation genome sequencing

towards personalized medicine
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Author: Search for this author Janitz, Michal [Hrsg.]
Year: 2008
Publisher: Weinheim, Wiley-VCH
Media group: Ausleihbestand
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Branch: Hauptstelle Locations: GE-40 259 Status: available Reservations: 0 Due date: Barcode: 00193232 Floor plans: Floor plan Lending note:

Content

Führende Experten aus der industriellen und akademischen Forschung fassen die neuesten Entwicklungen auf dem Gebiet der DNA-Sequenzierung zusammen und untersuchen, wie sich diese Neuerungen auf die Genomforschung, Wirkstoffentwicklung und das Gesundheitswesen (Stichwort: personalisierte Medizin) auswirken. Kommerziell verfügbare Plattformen werden ausführlich beschrieben und alternativen Verfahren gegenübergestellt. Neben den rein naturwissenschaftlich-medizinischen Fragen kommen auch soziale, ethische und wirtschaftliche Aspekte zur Sprache.
 
Aus dem Inhalt
SANGER DNA SEQUENCING
Sanger DNA sequencing (Men)
NEXT GENERATION SEQUENCING - TOWARDS PERSONALIZED MEDICINE
Illumina Genome Analyzer II System (Lakdawalla)
Applied Biosystems SOLiD? System - Ligation-based Sequencing (Prediger)
The next Generation Genome Sequencing: 454/Roche GS FLX (Egholm)
Polony Sequencing - History, technology, and Applications (Edwards)
THE BOTTLENECK: SEQUENCE DATA ANALYSIS
Next Generation Sequence Data Analysis (Bloksberg)
DNASTARs Next Generation Software (Durfee)
EMERGING SEQUENCING TECHNOLOGIES
Real-time DNA sequencing (Hardin)
Direct Sequencing by TEM of Z-substituted DNA Molecules (Glover)
A Single DNA Molecule Barcoding Method with Applications in DNA Mapping and Molecular Haplotyping (Xao)
Optical Sequencing - Acquisition from Mapped Single Molecule Templates (Schwartz)
Microchip-based Sanger Sequencing of DNA (Barron)
NEXT GENERATION SEQUENCING - TRULY INTEGRATED GENOME ANALYSIS
Multiplex Sequencing of Paired End diTags for Transcriptome and Genome Analysis (Ruan)
Palaeogenomics using the 454 Sequencing Platform (Gilbert)
ChIPSeq: Mapping of Protein-DNA Interactions (Fejes)
MicroRNA Discovery and Expression Profiling using Next-generation Sequencing (Cuppen)
DeepSAGE - Tag-based Transcriptome Analysis beyond Microarrays (Nielsen)
The new Genomics and Personal Genome Information: Ethical Issues (Lunshof)

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Details

Author: Search for this author Janitz, Michal [Hrsg.]
Statement of Responsibility: edited by Michal Janitz
Year: 2008
Publisher: Weinheim, Wiley-VCH
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Classification: Search for this systematic GE-40, ME-10
Subject type: Search for this subject type Monographien
ISBN: 9783527320905
ISBN (2nd): 3-527-32090-3
Description: XX, 260 S. : Ill., graph. Darst.
Tags: Genetik Methoden; Medizin allgemein
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Language: englisch||
Footnote: Literaturangaben
Media group: Ausleihbestand