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Introduction - Kaufmann/Kabelitz

 

The immune response to infectious agents

 

 

 

 

 

 

 

I. General Methods

 

Radbruch A - Phenotyping and isolation of functionally distinct leukocyte populations; Sch tze S - Magnetic isolation of subcellular compartments; Berzofsky J - Prediction of MHC ligands and T-cell epitopes; McMichael A - Quantitative analysis of T-cell responses; Schurr E - Genetics of susceptibility and resistance to infection; Wiker H - Proteomic approaches to study immunity in infection; Sioud M - siRNA as a tool to study immune responses in infection; Schr der JM - Isolation and characterization of antimicrobial peptides; Karin M - Toll - and NOD-like receptors in anti-infective immunity; von Andrian UH - Visualization of immune responses in vivo

 

 

 

 

 

 

 

II. Murine Models

 

 

 

A. In vitro analysis

 

 

 

Czuprynski CJ - Isolation of lymphocytes from infected animals; Busch DH - Killer cell assays; Kiyono H - Quantification of murine T-cell cytokine responses; Gordon S - Isolation and functional charactzerization of macrophages

 

 

 

 

 

 

 

B. In vivo analysis

 

 

 

Ehlers S - Measuring immune responses in vivo; Belkaid Y - Control of infection by regulatory T-cells; Stockinger B - Th17 cells in inflammation

 

C. Specific Models

 

 

 

Orme IM - Murine models of tuberculosis; Muller I - The leishmaniasis model; Autenrieth IB - Murine models of infection with extracellular bacteria; Flynn JL - Local immune responses in the lung; Romani L - Murine models of fungal infections; Powrie F - Immunity in the gut; Reddehase MJ - Murine cytomegalovirus infection; Lingnau K/von Gabain A - Boosting of immune responses by adjuvants

 

 

 

 

 

 

 

III. Human System

 

 

 

Banchereau J - Subpopulations of human dendritic cells; Yssel H - Measuring human cytokine responses; Seitzer U - Measuring immune responses in situ; Garcia JV - Humanized mice for the analysis of human immune responses

 

IV. Appendix

Benoist C - The NIH knock-out mouse project; Beutler B - Forward genetic analysis to understand innate immunity