Contents
Preface v
Contributors ix
1 Renal Cytochrome P450s and Flavin-Containing Monooxygenases: Potential Roles
in Metabolism
and Toxicity of 1,3-Butadiene, Trichloroethylene,
and Tetrachloroethylene
Adnan A. Elfarra
2 Experimental Approaches for the Study of Cytochrome P450 Gene Regulation
Hollie I. Swanson, S.D. Kraner, S.S. Ray, M. Hoagland,
E.D. Thompson, X. Zheng, and Y. Tian
3 Insulin and Growth Factor Signaling: Effects
on Drug Metabolizing Enzymes
Sang K. Kim, Kimberly J. Woodcroft,
and Raymond F. Novak
4 Catalytic Function and Expression of Glutathione
Transferase Zeta
Philip G. Board, M.W. Anders, and Anneke C. Blackburn
5 Glucuronidation of Fatty Acids and Prostaglandins
by Human UDP Glucuronosyltransferases
Anna Radominska-Pandya, Joanne M. Little,
and Arthur Bull
6 Transcriptional Regulation of UDP-Glucuronosyltransferases
Anna Radominska-Pandya, Peter I. Mackenzie,
and Wen Xie
7 Phenotypic and Genotypic Characterization
of N-Acetylation
Craig K. Svensson and David W. Hein
8 Methods and Approaches to Study Metabolism
and Toxicity of Acetaminophen
Sam A. Bruschi
9 Modulation of Drug Metabolism and Antiviral Therapies
Bernhard H. Lauterburg
10 Modulation of Thiols and Other Low-Molecular-Weight Cofactors: Effects
on Drug Metabolism
and Disease Susceptibility
Charles V. Smith
11 Multidrug Resistance Proteins and Hepatic Transport
of Endo- and Xenobiotics
Phillip M. Gerk and Mary Vore
12 Structural Determinants of Folate and Antifolate Membrane Transport by the
Reduced Folate Carrier
Wei Cao and Larry H. Matherly
13 Glutathione Transport in the Kidneys:
Experimental Models, Mechanisms, and Methods
Lawrence H. Lash
14 Human Cytosolic Sulfotransferases:
Properties, Physiological Functions, and Toxicology
Charles N. Falany
Index
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Statement of Responsibility:
edited by Lawrence H. Lash
Year:
2005
Publisher:
Totowa, NJ, Humana Press
Articles:
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Classification:
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ME-30, ME-20
ISBN:
1588293246
Description:
X, 387 S. : Ill., graph. Darst.
Language:
englisch||
Footnote:
Literaturangaben
Media group:
Ausleihbestand