Here is an important source for the advanced technologies of modern biotechnology. It encompasses with a wide range of topics. It highlights the roles of targeted delivery of polymeric nanodrugs to cancer cells and microbial detoxifying enzymes in bioremediation and bacterial plasmids in antimicrobial resistance, while also addressing modern trends such as pharmacogenomics, gene expression, recombinant proteins from methylotrophic yeast, novel fermentation inhibitors of bioethanol production, and polyhydroxyalkanoate-based biomaterials. The book also covers the practical utility of biotechnology and bioinformatics for bioenergy, environmental remediation, production of high value biochemicals, modeling molecular interactions, drug discovery, and healthcare and personalized medicine.
Modern biotechnology is an interdisciplinary, revolutionary, and beneficial branch of biology that encompasses various advanced techniques. In agriculture, biotechnology plays a crucial role for crop improvement to transfer genes between different plants to enhance characteristics such as yield and disease resistance. In healthcare, the role of biotechnology encompasses genetic testing, gene therapy, drug development, and pharmacogenomics. Bioengineering is the physical side of biotechnology that focuses on the genetic manipulation in the biological systems. In the current scenario, bioremediation and biodegradation play a crucial role by focusing on the design and development of technologies using microorganisms to cleanup environmental pollution. Application of biotechnological aspects with the knowledge of bioinformatics further leads to the development of newer technologies. In order to apply the knowledge of biotechnology, we need the support of bioinformatics to acquire relevant information of biological data. In the era of molecular medicine and personalized genomics, there needs to be an integration of genomic, cellular, molecular, and clinical data which are all possible through bioinformatics.
The book is aimed at graduates, scholars, biotechnology researchers, and bioinformatics professionals in applied biotechnology, bioengineering, biomedical sciences, microbiology and environmental sciences to broaden their knowledge about these newer tools, techniques, innovations, and applications.
CONTENTS:
Preface
Chapter 1: Polymeric Nanoparticle Mediated Targeted Drug Delivery to Cancer Cells
Gul-E-Saba and Mohd Azmuddin Abdullah (Malaysia)
Chapter 2: Pharmacogenetics and Pharmacogenomics in Personalized Medicine: Role of Gene Polymorphism in Drug Response
Rownock Afruza, Fumiaki Suzuki, and A. H. M. Nurun Nabi (Bangladesh, Japan)
Chapter 3: Natural History and Molecular Biology of Hepatitis B Virus
Essam Mohammed Janahi (Kingdom of Bahrain)
Chapter 4: Reconfigurable Parallel Platforms for Dependable Personalized Health Monitoring
Olufemi Adeluyi and Jeong A. Lee (Republic of South Korea)
Chapter 5: High Throughput Evaluation of Gene Expression from Formalin-Fixed Paraffin-Embedded Tissues
Paraskevi A. Farazi (Cyprus)
Chapter 6: Microbial Detoxifying Enzymes Involved in Biodegradation of Organic Chemopollutants
Pradnya Pralhad Kanekar and Seema Shreepad Sarnaik (India)
Chapter 7: An Insight Into Horizontal Gene Transfer Triggering Widespread Antimicrobial Resistance in Bacteria
Zakir Hossain (Bangladesh)
Chapter 8: Production and Biotechnological Applications of Recombinant Proteins by Methylotrophic Yeast: Past, Present and Future Perspectives
Marcos López-Pérez and Rina María González-Cervantes (Mexico)
Chapter 9: Mechanism of Tolerance and Engineering of Yeast Strain Resistant to Novel Fermentation Inhibitors of Bioethanol Production
Lahiru Niroshan Jayakody, Nobuyuki Hayashi, and Hiroshi Kitagaki (Japan)
Chapter 10: Biotechnological Potential of Alkaliphilic Microorganisms
Pradnya Pralhad Kanekar, Amaraja Abhay Joshi, Snehal Omkar Kulkarni, Suchitra Baburao Borgave, eema Shreepad Sarnaik, Smita Shrikant Nilegaonkar, Anita Satish Kelkar, and Rebecca Sandeep Thombre (India)
Chapter 11: Design and Tailoring of Polyhydroxyalkanoate-Based Biomaterials Containing 4-Hydroxybutyrate Monomer
Sevakumaran Vigneswari, Kesaven Bhubalan, and Abdullah Al-Ashraf Amirul (Malaysia)
Chapter 12: Algal Biotechnology for Bioenergy, Environmental Remediation and High-Value Biochemicals
Mohd Azmuddin Abdullah, Syed Muhammad Usman Shah, Ashfaq Ahmad, and Hamdy El-Sayed (Malaysia)
Chapter 13: Molecular Docking: A Practical Approach for Protein Interaction Analysis
Neil Andrew D. Bascos (Philippines)
Chapter 14: Application of Biotechnology and Bioinformatics in Drug Designing and Discovery
A. K. M. Mahbub Hasan, Sajib Chakrobarty, Rajib Chakrovorty, and A. H. M. Nurun Nabi (Australia, Bangladesh)
Chapter 15: Systems Biotechnology for Industrial Microorganisms
Ana M. Martins (United Arab Emirates)
Chapter 16: Bioinformatics and Biotechnology in Human Genetic Research: A Current Scenario
Sathiya Maran, Thirumulu Ponnuraj Kannan, and Teguh Haryo Sasongko (Malaysia)
Index