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NF-kappaB in health and disease

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Year: 2011
Publisher: Berlin, Springer
Series: Current topics in microbiology and immunology; Volume 349
Media group: Serien
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Content

This volume is focused on a transcription factor that started its life as a B cell-specific nuclear protein, but has matured to become one of the most extensively studied transcriptional regulators, found to control many pathophysiological processes: NF-kB. Articles in the volume, all of them written by the leading experts in the field, range from description of the NF-kB system and its basic components, its logic and its transcriptional regulatory functions to its participation in diverse processes, including inflammation, immunity, mucosal homeostasis and cancer. In addition to discussing the molecular biology and physiology of the NF-kB system, this volume also addresses the therapeutic targeting of NF-kB and its regulators. Thus, this volume is an important reading to both basic and translational scientists interested in different aspects of this highly versatile regulatory system.

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Statement of Responsibility: Michael Karin, editor
Year: 2011
Publisher: Berlin, Springer
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Classification: Search for this systematic ZB-90, MB-40
Subject type: Search for this subject type Sammelwerk
ISBN: 9783642160165
ISBN (2nd): 3-642-16016-6
Description: VIII, 268 S. : Ill., graph. Darst.
Series: Current topics in microbiology and immunology; Volume 349
Tags: Immunbiologie; Medizinische Mikrobiologie
Participating parties: Search for this character Karin, Michael [Hrsg.]
Language: englisch||
Footnote: Literaturangaben
Media group: Serien