This unique book integrates knowledge from a wide range of expertise, specifically applied to the mouse and addressed at a wide audience from those new to the field to experts who want an update on the state of the art. Mouse Genetics and Transgenics: A Practical Approach covers all aspects of using the mouse as a genetic model organism: care and husbandry; archiving stocks as frozen embryos or sperm; making new mutations by chemical mutagenesis; transgenesis; gene targeting; mapping mutations and polygenic traits by cytogenetic, genetic, and physical means; and disseminating and researching information via the Internet.
List of Contributors
Abbreviations
1. Mouse care and husbandry, Colin M. Hetherington, Brendan Doe, and Donald Hay
2. Cryopreservation and rederivation of embryos and gametes, Peter H. Glenister and William F. Rall
3. Spatial analysis of gene expression, Stefan G. Nonchev and Mark K. Maconochie
4. Mapping phenotypic trait loci, Benjamin A. Taylor
5. Mapping genomes, Paul Denny and Stephen D. M. Brown
6. Mouse cytogenetics and FISH, Ellen C. Akeson et al.
7. Electronic tools for accessing the mouse genome, Janan T. Eppig
8. Mutagenesis of the mouse germline, Monica J. Justice
9. Generation of transgenic mice from plasmids, BACs and YACs, Annette Hammes and Andreas Schedl
10. Directed mutagenesis in embryonic stem cells, Antonius Plagge, Gavin Kelsey and Nicholas D. Allen
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Statement of Responsibility:
ed. by Ian J. Jackson and Catherine M. Abbott
Year:
2000
Publisher:
Oxford, Oxford Univ. Pr.
Articles:
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ISBN:
0199637083
ISBN (2nd):
0-19-963709-1
Description:
XXIV, 297 S. : Ill., graph. Darst.
Language:
englisch||
Footnote:
Literaturangaben
Media group:
Dauerleihe