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Histopathology of preclinical toxicity studies

interpretation and relevance in drug safety studies

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Author: Greaves, Peter

Year: 2015

Publisher: Amsterdam [u.a.], Elsevier

Dauerleihe

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Branch	Locations	Status	Reservations	Due date	Barcode	Floor plan	Lending note
Branch: Dauerleihe	Locations: ME-20 95	Status: borrowed	Reservations: 0	Due date: 1/1/2199	Barcode: 00273180	Floor plans: Floor plan	Lending note:

Content

The new 4th edition of Histopathology of Preclinical Toxicity Studies is now completely in full color and continues to describe the pathology found in drug safety studies in laboratory animals with an evidence-based discussion of the relevance of these findings to the clinical investigation of new drugs for humans. Organized according to organ systems, this revision features a thoroughly updated bibliography and discusses new drug-induced pathologies and applicable species comparisons to aid in the preclinical safety assessment of new medicines. This updated reference is essential for those involved in drug safety evaluation, including pathologists, toxicologists and pharmacologists working in corporate, government, academic and research settings.

TOC:

Chapter 1: Introduction

Chapter 2: Integumentary System

- Skin and subcutaneous tissue

Chapter 3: Mammary Gland

Chapter 4: Haemopoietic and Lymphatic Systems

- Blood/bone marrow

- Lymphoid system

- Lymph nodes

- Spleen

- Thymus

- Lymphoreticular neoplasms

Chapter 5: Musculoskeletal System

- Bone

- Joints

- Skeletal muscle

Chapter 6: Respiratory Tract

- Nose, nasal sinuses, nasopharynx and pharynx

- Larynx and trachea

- Bronchi and lungs

Chapter 7: Cardiovascular System

- Heart and pericardium

- Systemic blood vessels

- Pulmonary blood vessels

Chapter 8: Gastrointestinal tract

- Forestomach

- Stomach (glandular)

- Small intestine

- Large intestine

Chapter 9: Liver and Pancreas

- Liver

- Bile ducts, biliary system

- Pancreas

Chapter 10: Urinary System

- Kidney

- Urinary bladder

Chapter 11: Male Genital Tract

- Prostate gland

- Epididymis

- Testis

Chapter 12: Female Genital Tract

- Vagina

- Cervix

- Uterus

- Ovary

Chapter 13: Endocrine System

- Pituitary gland

- Adrenal gland

- Thyroid gland

- Parathyroid gland

Chapter 14: Nervous System and Special Sense Organs

- Brain

- Spinal cord, spinal nerve roots, peripheral nerves

- Eye

- Ear

Subject index

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Details

Author: Greaves, Peter

Statement of Responsibility: Peter Greaves

Year: 2015

Publisher: Amsterdam [u.a.], Elsevier

Classification: ME-20, BI-30, ZB-40

Subject type: Handbuch

ISBN: 978-0-444-53856-7

ISBN (2nd): 0-444-53856-9

Description: 4. edition, reprinted, VI, 886 S. : Ill., graph. Darst.

Tags: Toxikologie; Pharmakologie; Zoologie; Histologie

Language: Englisch

Footnote: Literaturangaben

Media group: Dauerleihe

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