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Actin-binding proteins and disease

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Year: 2008
Publisher: New York [u.a.], Springer
Series: Protein reviews; 8
Media group: Ausleihbestand
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Branch: Hauptstelle Locations: NA-30 159 Status: available Reservations: 0 Due date: Barcode: 00185892 Floor plans: Floor plan Lending note:

Content

Table of contents
 
Overview of actin.- Actin Genetic Diseases.- Actin-binding drugs.- Filamentous actin as an autoantigen.- Actin Binding Protein Function and its Relation to Disease Pathology.- ADF/cofilin, actin dynamics and disease.- Gelsolin and disease.- Profilin and disease.- The roles of thymosin beta4 in cell migration and cell-to-cell signalling in disease.- Actin and actin binding proteins in cancer progression and metastasis.- Defects in actin and actin-binding proteins in leukocytes.- The role of PIP2 in actin, actin-binding proteins and disease.- Intracellular pathogens and the actin cytoskeleton.- Actin and its binding proteins in heart failure.
 
About this book
 
This volume, written by experts in the field, is the first to deal with the relationship between human disease and the actin cytoskeleton. It provides overviews of actin and selected actin-binding proteins, and then focuses on diseases that involve these proteins. Specific chapters deal with actin, cofilin, profilin, gelsolin and thymosin Ÿ4. Other chapters discuss the roles of multiple actin-binding proteins in cancer and metastasis, leukocyte disorders, and heart failure, and there is a chapter that describes how intracellular pathogens use the host actin cytoskeleton. This seminal volume is intended for researchers, clinicians, physicians, and graduate students in the fields of biochemistry, cell biology, microbiology, immunology, and genetics.

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Statement of Responsibility: Cristobal G. dos Remedios ; Deepak Chhabra editors
Year: 2008
Publisher: New York [u.a.], Springer
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Classification: Search for this systematic NA-30, ZB-90, ZB-100
Subject type: Search for this subject type Monographien
ISBN: 9780387717470
Description: XIV, 348 S. : Ill., graph. Darst.
Series: Protein reviews; 8
Tags: Proteine; Naturstoffe; Transformierte Zellen; Immunbiologie; Zellbiologie; Immunology
Participating parties: Search for this character Remedios, Cristobal G. dos [Hrsg.]; Chhabra, Deepak [Hrsg.]
Language: englisch||
Footnote: Literaturangaben
Media group: Ausleihbestand