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A statistical approach to genetic epidemiology

with access to e-learning platform by Friedrich Pahlke
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Author: Search for this author Ziegler, Andreas (creator); König, Inke R. (creator)
Year: 2010
Publisher: Weinheim, Wiley-VCH-Verl.
Media group: Ausleihbestand
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The pace of discovery in human genetics over the past three years has been extraor-dinary. Before, family- and population-based studies had identified a handfulof genetic markers associated with complex human traits and diseases. Now overmarkers associated with overtraits are known, and it seems every issueof the top genetics journals contains at least one paper linking a new locus to aclinically-relevant trait.The pace of technological change has also been exceptional. The Human GenomeProject took years to produce billion basepairs of sequence; a single wellequipped-lab can now produce that much sequence in a week.While these are exciting times for researchers interested in human genetics, theyare also challenging times–especially for students, teachers, and textbook authors.When a paper can go from cutting edge to pass ´e in the time from submission toreview, how much more difficult to keep a textbook current!Drs. Ziegler and K ¨onig have done a great service by thoroughly updating and revis-ing their textbook. The second edition touches on the most important developmentsof the last few years, most notably the success of genome-wide association studies.And it keeps the strengths of the previous edition, which include its compatibilitywith the classroom (see, e.g., the companion web course and the exercises) and thelist of internet resources at the end of each chapter. These references are important,because publicly available databases like dbSNP, the HapMap andGenomesProject are central to the practice of modern genetic epidemiology.

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Author: Search for this author Ziegler, Andreas (creator); König, Inke R. (creator)
Statement of Responsibility: Andreas Ziegler and Inke R. König
Year: 2010
Publisher: Weinheim, Wiley-VCH-Verl.
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Classification: Search for this systematic ME-40
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ISBN: 9783527323890
Description: Second edition, XXIV, 497 S., graph. Darst.
Tags: Erbkrankheit; Humangenetik; Epidemiologie; Biostatistik; Epidemie; Statistische Analyse; Biostatistics.; Statistics for Life Sciences, Medicine, Health Sciences.
Participating parties: Search for this character Ziegler, Andreas; König, Inke R.
Language: Deutsch, Englisch
Footnote: Literaturangaben. - Zusätzliches Online-Angebot unter www.wiley-vch.de/home/geneticepidemiology
Media group: Ausleihbestand