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IgM and its receptor and binding proteins

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Year: [2017]
Publisher: Cham, Springer International Publishing AG
Series: Current topics in microbiology and immunology; 408
Media group: Serien
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Branch: Hauptstelle Locations: Serie Status: available Reservations: 0 Due date: Barcode: 00300322 Floor plans: Floor plan Lending note:

Content

This volume reviews the current state of research on the IgM antibody and its multiple receptors and binding proteins. Interactions of the IgM ligands with these molecules are important for protection against infections as a first line of defense, as well as for regulation of immune responses to pathogens and self-antigens. The book includes up-to-date information on: (i) the phylogeny of three IgM-binding receptors [polymeric Ig receptor (pIgR), Fc receptor for both IgA and IgM (Fca/µR), and Fc receptor for IgM only (FcµR)]; (ii) the lymphocyte-restricted distribution and unique ligand-binding activity of FcµR; (iii) the definition and potential function of Fc receptor-like molecule A (FCRLA) as a resident endoplasmic reticulum protein that binds IgM, but also IgG and IgA; (iv) IgM antibody-mediated enhancement of humoral immune responses, highlighting the importance of complement and its receptors, (v) the numerous important roles of IgM natural antibodies in regulation of inflammation. It is an invaluable resource for researchers and clinicians alike.

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Search for this author
Year: [2017]
Publisher: Cham, Springer International Publishing AG
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Classification: Search for this systematic MB-40, ZB-90
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ISBN: 9783319645247
ISBN (2nd): 3319645242
Description: ix, 117 Seiten, Illustrationen, Diagramme
Series: Current topics in microbiology and immunology; 408
Tags: Medizinische Mikrobiologie; Immunbiologie
Participating parties: Search for this character Kubagawa, Hiromi (editor); Burrows, Peter D. (editor)
Language: Deutsch
Media group: Serien