Principles of Mucosal Immunology is designed for graduate students and postdoctoral fellows, researchers in immunology and microbiology, and medical and dental students. It presents the basic and clinical aspects of the mucosal immune system, focusing on the major components of the mucosal barrier—the gastrointestinal, upper and lower respiratory, ocular, and genitourinary mucosal immune systems. Topics include the development and structure of the mucosal immune system and its cellular constituents, host-microbe relationships, infection, mucosal diseases, and vaccines. Principles of Mucosal Immunology is sponsored by the Society for Mucosal Immunology and is written by internationally recognized leaders in the field.
TOC:
I. Development and Structure of Mucosal Tissue
1. Overview of the Mucosal Immune System Structure
2. Phylogeny of the Mucosal Immune System
3. Immunological and Functional Differences Among Individual Compartments of the Mucosal Immune System
4. Secreted Effectors of the Innate Mucosal Barrier
II. Cellular Constituents of Mucosal Immune Systems and Their Function in Mucosal Homeostasis
5. Immune Function of Epithelial Cells
6. Intraepithelial Lymphocytes: Unusual T Cells at Epithelial Surfaces
7. Lymphocyte Populations within the Lamina Propria
8. Mucosal B Cells and Their Function
9. Secretory Immunoglobulins and Their Transport
10. Role of Dendritic Cells in Integrating Immune Responses to Lumenal Antigens
11. Intestinal Macrophages in Defense of the Mucosa
12. Mucosal Basophils, Mast Cells, and Eosinophils
13. M Cells and the Follicle-Associated Epithelium
14. Lymphocyte Trafficking from Inductive Sites to Effector Sites
15. Mucosal Tolerance
III. Microbial Commensalism
16. Recognition of Microbe-Associated Molecular Patterns by Pattern Recognition Receptors
17. The Commensal Micorbiota and Its Relationship to Homeostasis and Disease
IV. Genitourinary Tract
18. The Immune System of the Genitourinary Tract
19. Mucosal Immune Responses to Microbes in the Genitourinary Tract
V. Nose, Airways, Oral Cavity, and Eyes
20. Immunobiology of the Nose, Upper Airways, and Oral Cavity
21. Bronchial Associated Lymphoid Tissue and Immune-mediated Respiratory Diseases
22. The Ocular Surface as a Mucosal Immune Site
VI. Infectious Diseases of Mucosal Surfaces
23. Mucosal Interactions with Enteropathogenic Bacteria
24. Heliobacter pylori Infection
25. Viral Infections
26. Infection-driven Periodontal Disease
27. Vaccine Strategies for Mucosal Infections
VII. Specific Immune-mediated Diseases of Mucosal Surfaces
28. Celiac Disease
29. IgA Nephropathy
30. Mucosal Manifestations of Immunodeficiencies
31. Inflammatory Bowel Disease
32. Food Sensitive and Eosinophilic Enteropathies