1. Immunostimulatory DNA: An Overview
Eyal Raz
pp. 3-8
2. Historical Perspectives
Saburo Yamamoto; Toshiko Yamamoto; Tohru Tokunaga
pp. 9-14
3. Signal Transduction Pathways Activated By CpG-DNA
Hans Häcker
pp. 17-38
4. A Novel Toll-Like Receptor that Recognizes Bacterial DNA
Hiroaki Hemmi; Shizuo Akira
pp. 39-47
5. Activation of Innate Immunity by Microbial Nucleic Acids
Wen-Ming Chu; Xing Gong; Tony Yoon
pp. 49-61
6. Phosphorothioate Backbone Modification to Changes the Pattern of Responses CpG Motifs
Katryn Stacey; David Sester; Shalin Naik; Tara Roberts; Matthew Sweet; David Hume
pp. 63-77
7. Activation of NK Cell By Immunostimulatory Oligo-DNA in Mouse and Human
Saburo Yamamoto; Toshiko Yamamoto; Tetsuro Kataoka; Sumiko Iho; Tohru Tokunaga
pp. 81-89
8. Regulation of Antigen Presenting Cell Function by CpG DNA
David Askew; Rose Chu; Clifford Harding
pp. 91-101
9. Activation of B cells by CpG Motifs in Bacterial DNA
Ae-Kyung Yi; Arthur Krieg
pp. 103-127
10. IFN-Dependent Pathways for Stimulation of Memory CD8+ Cells
Jonathan Sprent
pp. 129-135
11. Cross-Priming of CD8+ T Cells by Immunostimulatory Sequence DNA
Hearn Cho; Sandip Datta; Eyal Raz
pp. 137-149
12. The Th1 Adjuvant Effect of Immunostimulatory (ISS) DNA Sequences
Maripat Corr; Chih Tang
pp. 153-162
13. Immunostimulatory DNA Prepriming for the Induction of Th1 and Prevention of Th2 Biased Immune Responses
Hiroko Kobayashi; Elena Martin-Orozco; Kenji Takabayashi; Anthony Horner
pp. 163-174
14. Protein-Immunostimulatory DNA-Conjugate: A Novel Immunogen
Kenji Takabayashi; Helen Tighe; Lucinda Beck; Hans Spiegelberg
pp. 175-188
15. Immunostimulatory DNA Sequence Based Mucosal Vaccines
Anthony Horner
pp. 189-202
16. Enhancement of the Immunoadjuvant Activity of Immunostimulatory DNA Sequence By Liposomal Delivery
Eli Kedar; Igal Louria-Hayon; Aviva Joseph; Zichria Zakay-Rones; Tomoko Hayashi; Kenji Takabayashi; Yechezkel Barenholz
pp. 203-218
17. Immunostimulatory Sequences in Plasmid Vectors
Christina Wu; Chih Tang; Brian Crain; Maripat Corr
pp. 219-226
18. Comparison of CpG DNA with Other Adjuvants for Vaccination Against Hepatitis B
Michael McCluskie; Risini Weeratna; Heather Davis
pp. 229-238
19. Immunostimulatory DNA-Based Immunization: Hope for an HIV Vaccine?
Sandip Datta; Anthony Horner; Kenji Takabayashi; Eyal Raz
pp. 239-254
20. Immunoprotective Activity of CpG Oligonucleotides
Dennis Klinman; Ken Ishii; Ihsan Gursel
pp. 255-263
21. Protective Immunity of Immunostimulatory Sequences Against Mycobacterial Infection
Tomoko Hayashi; Christine Tran; Lucinda Beck; Savita Rao; Antonino Catanzaro
pp. 265-275
22. DNA-Based Immunotherapeutics For Allergic Disease
Anthony Horner; Eyal Raz
pp. 279-287
23. Immunostimulatory DNA for Allergic Asthma
Reid Ikeda; Kenji Takabayashi; David Broide
pp. 289-299
24. CpG Oligodeoxynucleotides in Asthma
Kunihiko Kitagaki; Joel Kline
pp. 301-314
25. Modulation of Allergic Conjunctivitis by Immunostimulatory DNA Sequence Oligonucleotides
Andrea Keane-Myers; Chi-Chao Chan
pp. 315-325
26. CpG Oligodeoxynucleotides and Monoclonal Antibody Therapy of Lymphoma
Thomas Warren; George Weiner
pp. 329-337
27. The Antigenicity of Bacterial DNA
David Pisetsky
pp. 341-350
28. Inflammatogenic Properties of Immunostimulatory DNA Sequences
Andrej Tarkowski; L. Collins; Guo-Min Deng; Lena Mölne
pp. 351-361
29. The Role of Immunostimulatory DNA Sequences in Arthritis
Sarah Roord; Arash Ronaghy; Berent Prakken; Kenji Takabayashi; Dennis Carson
pp. 363-371
30. Effects of Immunostimulatory DNA Oligonucleotides on Experimental Colitis
Daniel Rachmilewitz; Fanny Karmeli; Leonor Leider-Trejo; Kenji Takabayashi; Tomoko Hayashi; Eyal Raz
pp. 373-384
31. CpG-ODNSafety Considerations
Daniela Verthelyi; Dennis Klinman
pp. 385-396