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Our immune system is a complex network of cells continually battling against a barrage of attacks from our environment, quite literally to save our lives. But what protects us from the potentially life-threatening microorganisms that surround us every day?

 

In the lucid, accessible style for which John Playfair is renowned, and together with Greg Bancroft, an expert in infectious diseases, Infection and Immunity explains how our immune system defends us. The authors describe the main causes of infection that our bodies have to battle against - from bacteria to viruses, fungi to protozoa - and explains the intricate and fascinating ways in which we respond, from detection of potentially dangerous organisms to their ultimate elimination - sometimes, unfortunately, suffering new pathological symptoms in the process.

 

Presenting a fully-rounded, well-balanced overview of the field, the book also explains how diseases spread, and what measures we can take to control this spread - from vaccination to increasing awareness through public health initiatives.

 

With examples of infectious diseases from across the world, Infection and Immunity is the ideal text for biomedical science, bioscience, and microbiology students who need to understand the basics of what causes infection, and how our immune systems respond.

TOC:

The infectious organisms

1: Introduction: parasites, pathogens, and immunity

2: Viruses

3: Bacteria

4: Fungi

5: Protozoa

6: Helminths (worms)

7: Ectoparasites

8: Prions

9: Disease: virulence and susceptibility

The immune system

10: Defence, immunity, the immune system

11: External defences: entry and exit

12: Innate immunity

13: How pathogens escape innate immunity

14: Disease due to innate immunity

15: Immunodeficiency I: primary defects of innate immunity

16: Adaptive immunity: introduction

17: B cells and antibody

18: T cells and the MHC

19: The antibody response

20: Cell-mediated responses

21: Regulation of immune responses and memory

22: How pathogens escape adaptive immunity

23: Disesase due to adaptive immunity I: hypersenstivity

24: Disease due to adaptive immunity II: autoimmunity

25: Immunodeficiency II: primary defects of adaptive immunity

26: Immunodeficiency III: secondary immunodeficiency and AIDS

The host-pathogen balance

27: Epidemiology

28: Control of infectious disease: vaccination

29: Control of infectious disease: chemotherapy

30: Control of infectious disease: public health measures

31: Viral and prion disease and immunity

32: Bacterial disease and immunity

33: Fungal disease and immunity

34: Protozoal disease and immunity

35: Helminth disease and immunity

36: Ectoparasites and immunity

37: Emerging and future infectious diseases