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Janeway's Immunobiology, Seventh Edition is an introductory text for use in immunology courses for undergraduates, graduate students and medical students. It guides the reader through the immune system in all its aspects - from the first engagement of innate immunity to the generation of the adaptive immune response and its clinical consequences. The Seventh Edition has been comprehensively updated throughout, and includes new information on topics such as NK cells, Toll-like receptors, AID, viral evasins, mucosal immunity, and celiac disease, to name a few. Each copy of the book includes a revised CD-ROM, Immunobiology Interactive, which contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes. Janeway's Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, full-color art program, scientific accuracy and consistent viewpoint - that of the host's interaction with an environment containing many species of potentially harmful microorganisms.

Table of Contents

 

Part I An Introduction to Immunobiology and Innate Immunity

 

Chapter 1 Basic Concepts in Immunology

 

Chapter 2 Innate Immunity

 

Part II The Recognition of Antigen

 

Chapter 3 Antigen Recognition by B-cell and T-cell Receptors

 

Chapter 4 The Generation of Lymphocyte Antigen Receptors

 

Chapter 5 Antigen Presentation to T Lymphocytes

 

Part III The Development of Mature Lymphocyte Receptor Repertoires

 

Chapter 6 Signaling Through Immune System Receptors

 

Chapter 7 The Development and Survival of Lymphocytes

 

Part IV The Adaptive Immune Response

 

Chapter 8 T Cell-Mediated Immunity

 

Chapter 9 The Humoral Immune Response

 

Chapter 10 Dynamics of Adaptive Immunity

 

Chapter 11 The Mucosal Immune System

 

Part V The Immune System in Health and Disease

 

Chapter 12 Failures of Host Defense Mechanism

 

Chapter 13 Allergy and Hypersensitivity

 

Chapter 14 Autoimmunity and Transplantation

 

Chapter 15 Manipulation of the Immune Response

 

Part VI The Origins of Immune Responses

 

Chapter 16 Evolution of the Immune System

 

Appendix I Immunologists’ Toolbox

 

Appendix II CD Antigens

 

Appendix III Cytokines and their Receptors

 

Appendix IV Chemokines and their Receptors

 

Appendix V Immunological Constants

 

Biographies

 

Glossary

 

Index