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Kurzbeschreibung

zur Hausen provides a thorough and comprehensive reference for all oncologists, microbiologists and molecular biologists researching the relationships between infections and cancer.

 

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HISTORICAL REVIEW

The Early Period (1898-1911)

Frustration and Successes (1912-1950)

The Period from 1950 to 1965

A First Human Tumor Virus?

The Difficult 1970s

The Re-emergence of a Concept

THE QUEST FOR CAUSALITY

Infectious Agents as Direct Carcinogens

Infectious Agents as Indirect Carcinogens

TUMORS LINKED TO INFECTIONS - SOME GENERAL ASPECTS

Tumor Types Linked to Infections

Global Contributions of Infections to Human Cancer

Host Interactions with Potentially Carcinogenic Infections

HERPESVIRUSES AND ONCOGENESIS

Alphaherpesviridae

Betaherpesviridae

Gammaherpesviridae

PAPILLOMAVIRUSES - A MAJOR CAUSE OF HUMAN CANCERS

Introduction

Concept of Viral Interfering Cascades

Cancers Linked to HPV Infections

Role of Co-factors

Preventive Vaccination

Therapeutic Vaccination

Therapy

HEPADNAVIRUS FAMILY

Hepatitis B Virus

Animal Hepadnaviruses

FLAVIVIRUS FAMILY

Hepatitis C Virus

RETROVIRUS FAMILY

Human T-lymphotropic Retroviruses 1 (HTLV-1)

Human T-lymphotropic Retroviruses 2 (HTLV-2)

Human Endogenous Retroviruses

Gibbon Ape Leukaemia Virus and Simian Sarcoma Virus

OTHER VIRUS INFECTIONS POSSIBLY INVOLVED IN HUMAN CANCERS

Polyomaviruses (JC, BK and SV40)

HELICOBACTER, CHRONIC INFLAMMATION AND CANCER

Discovery, Taxonomy and Genomics

Life Cycle, Specificity, and Virulence Determinants in Cancer Development

Prevention of H. Pylori Induced Cancer

Animal Models

Virulence Determinants of Enterohepatic Helicobacter Spp

Enterohepatic Helicobacter Spp. - Are they Cocarcinogens?

PARASITES AND HUMAN CANCER

Schistosomiasis

Infection with Liver Flukes (Opisthorchis Viverrini, O. Felineus, Clonorchis Sinensis)

CANCERS WITH A POSSIBLE INFECTIOUS ETIOLOGY

Leukemias and Lymphomas

Human Breast Cancer

Other Human Cancers Possibly Linked to Infectious Events