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Immunology, 8th Edition makes it easy for you to learn all the basic and clinical concepts you need to know for your courses and USMLEs. This medical textbooks highly visual, carefully structured approach makes immunology simple to understand and remember.

TOC:

Preface vii

 

List of Contributors ix

 

SECTION 1

 

Components of the Immune System 1

 

1 Introduction to the Immune System 3

 

David Male

 

2 Cells, Tissues, and Organs of the

 

Immune System 17

 

Peter M Lydyard and Nino Porakishvili

 

3 Antibodies 51

 

Roy Jefferis

 

4 Complement 71

 

B Paul Morgan

 

5 T Cell Receptors and MHC Molecules 89

 

David B Roth

 

SECTION 2

 

Modes of Immune Response 107

 

6 Mechanisms of Innate Immunity 109

 

David Male

 

7 Mononuclear Phagocytes in Immune

 

Defense 125

 

Luisa Martinez-Pomares and

 

Siamon Gordon

 

8 Antigen Presentation 143

 

David Male

 

9 Cell Cooperation in the Antibody

 

Response 157

 

Joseph C Marini and Kalpit A Vora

 

10 Cell-mediated Cytotoxicity 171

 

Victoria Male

 

11 Regulation of the Immune Response 183

 

David Bending

 

12 Immune Responses in Tissues 199

 

David Male

 

SECTION 3

 

Defense Against Infectious Agents 209

 

13 Immunity to Viruses 211

 

Persephone Borrow and Anthony A Nash

 

14 Immunity to Bacteria and Fungi 223

 

Gregory J Bancroft

 

15 Immunity to Protozoa and Worms 243

 

Richard J Pleass

 

16 Primary Immunodeficiencies 263

 

Luigi D Notarangelo

 

17 AIDS, Secondary Immunodeficiency

 

and Immunosuppression 277

 

Dean H Kedes and Lisa A Nichols

 

18 Vaccination 289

 

Colin Casimir

 

SECTION 4

 

Immune Responses Against Tissues 305

 

19 Immunological Tolerance 307

 

Thomas Kamradt

 

20 Autoimmunity and Autoimmune

 

Disease 323

 

James E Peters and David A Isenberg

 

21 Transplantation and Rejection 341

 

Andrew J T George

 

22 Immunity to Cancers 355

 

Pramod K Srivastava

 

V

 

SECTION 5

 

Hypersensitivity 369

 

23 Immediate Hypersensitivity (Type I) 371

 

Thomas A E Platts-Mills

 

24 Hypersensitivity (Type II) 393

 

David Male

 

25 Hypersensitivity (Type III) 405

 

David P DCruz

 

26 Hypersensitivity (Type IV) 419

 

Warwick J Britton

 

Appendices online

 

1. Major Histocompatibility Complex

 

2. CD System

 

3. The Major Cytokines

 

4. Human Chemokines and Their Receptors

 

Critical thinking: Explanations 433

 

Glossary 445

 

Index 455

 

vi

 

Contents