Contents
Preface
Contributors
PART I. INTRODUCTION
1. Susceptibility Testing Methods of Antifungal Agents
Erika J. Ernst
Part II. Antifungal Resistance
2. DNA Fingerprinting Methods for Candida Species
Shawn R. Lockhart, Claude Pujol, Andrew R. Dodgson,
and David R. Soll
3. CARE-2 Fingerprinting of Candida albicans Isolates
Joachim Morschhäuser, Peter Staib, and Gerwald Köhler
4. Targeted Gene Deletion in Candida albicans Wild-Type Strains
by MPAR Flipping
Joachim Morschhäuser, Peter Staib, and Gerwald Köhler
5. Application of DNA Microarray Analysis to the Study of Azole
Antifungal Resistance in Candida albicans
Katherine S. Barker and P. David Rogers
6. Application of Proteomic Analysis to the Study of Azole Antifungal Resistance in Candida albicans
Massoumeh Z. Hooshdaran, George M. Hilliard,
and P. David Rogers
7. Techniques for Antifungal Susceptibility Testing
of Candida albicans Biofilms
Gordon Ramage and José Luis López-Ribot
PART III. ANTIFUNGAL DEVELOPMENT AND EVALUATION
8. Natural Products and Antifungal Drug Discovery
Melissa R. Jacob and Larry A. Walker
9. Animal Model of Disseminated Candidiasis
David Andes
10. Murine Model of Invasive Aspergillosis
Russell E. Lewis and Nathan P. Wiederhold
11. Antifungal Combinations
Roxana G. Vitale, Javier Afeltra, and Eric Dannaoui
12. Post-Antifungal Effect Methods
Roxana G. Vitale
PART IV. HOST RESPONSE AND IMMUNOTHERAPY
13. Evaluation of Immunotherapy in Invasive Candidiasis:
Antifungal Activity and Cytokine Expression Assays
Maria Simitsopoulou and Emmanuel Roilides
14. Interaction of Histoplasma capsulatum With Human Macrophages, Dendritic Cells, and Neutrophils
Simon L. Newman
15. Immunology of Infection Owing to Cryptococcus neoformans
Floyd L. Wormley, Jr. and John R. Perfect
Index