Krebs steht bei den Todesursachen weltweit an zweiter Stelle. Die Forschung konzentriert sich zunehmend darauf, die Entstehung von Krebs ganzheitlich zu betrachten, bekannte Krebsmedikamente auf den Prüfstand zu stellen und Medikamente und kombinierte Therapieansätze zu entwickeln.
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Contributors.
Preface.
SECTION I: DEVELOPMENT OF ANTICANCER THERAPEUTICS.
1. Exploring the potential of natural products in cancer treatment (Fotini N. Lamari and Paul Cordopatis).
2. Combinatorial approach to anticancer drug design (Sotiris Missailidis).
3. Rational approaches to anticancer drug design/in silico drug development (Stefano Alcaro, Anna Artese and Francesco Ortuso).
SECTION II: ANTICANCER THERAPEUTICS.
4. Introduction (Teni Boulikas).
5. Platinum drugs (Teni Boulikas, Alexandros Pantos, Evagelos Bellis and Petros Christofis).
6. Antimicrotubule agents (Iain Brown, Jay N Sangrithi-Wallace and Andrew C Schofield).
7. Antimetabolites in cancer therapy (Jessica Scaiffe and David Kerr).
8. Antitumour antibiotics (Manuel M. Paz).
9. Alkylating agents (Ana Paula Francisco, Maria de Jesus Perry, Eduarda Mendes and Rui Moreira).
10. Hormone therapies (George C. Zografos, Nikolaos V. Michalopoulos and Flora Zagouri).
11. Photodynamic therapy of cancer (K. Eszter Borbas and Dorothée Lahaye).
12. Target-directed drug discovery (Tracey Bradshaw).
13. Tumour hypoxia: a malignant mediator (Jill L. O'Donnell, Aoife M. Shannon, David Bouchier-Hayes).
14. Resistance to chemotherapy drugs (Robert O?Connor and Laura Breen).
15. Cancer immunotherapy (Maria Belimezi).
16. Gene therapy (Maria Belimezi, Teni Boulikas and Michael L. Roberts).
17. Antisense agents (Huma Khan and Sotiris Missailidis).
18. Aptamers as anticancer agents (Vaidehi Makwana, Suzanne Simmons and Sotiris Missailidis).
SECTION III: OTHER ASPECTS IN ANTICANCER THERAPEUTIC DEVELOPMENT.
19. Treatment of cancer in conjunction with other agents (Gary Robert Smith).
20. Clinical trials in oncology (Tim Friede, Janet Dunn and Nigel Stallard).
21. Representative cancers, treatment and market (Teni Boulikas).
22. Conclusions and prospects (Sotiris Missailidis).
04707231063ENIntroduction.
1. Can Computer Games Affect Your Health?
2. Can Computer Games Change the Way You Think?
3. Can Computer Games Change Who You Are?
4. Can Computer Games Turn You Into an Addict?
5. Can Computer Games Make You Violent?
6. Can Computer Games Change the Way You Learn?
7. Can Computer Games Change Your Beliefs?
8. Can Computer Games Change Your Future?