Zweigstelle	Standorte	Status	Vorbestellungen	Frist	Barcode	Lageplan	Ausleihhinweis
Zweigstelle: Hauptstelle	Standorte: GE-30 49c	Status: Verfügbar	Vorbestellungen: 0	Frist:	Barcode: 00183660	Lagepläne: Lageplan	Ausleihhinweis:

Description

 

The third edition of the landmark text Recombinant DNA offers an authoritative, accessible, and engaging introduction to modern, genomecentered biology from its foremost practitioners. The new edition explores core concepts in molecular biology in a contemporary inquirybased context, building its coverage around the most relevant and exciting examples of current research and landmark experiments that redefined our understanding of DNA. As a result, students learn in a compelling way how working scientists make real highimpact discoveries.

 

The first chapters provide an introduction to the fundamental concepts of genetics and genomics, an inside look at the Human Genome Project, bioinformatic and experimental techniques for largescale genomic studies, and a survey of epigenetics and RNA interference. The final chapters cover the quest to identify diseasecausing genes, the genetic basis of cancer, and DNA fingerprinting and forensics. In these chapters the authors provide examples of practical applications in human medicine, and discuss the future of human genetics and genomics projects.

 

Contents

 

FOUNDATIONS OF DNA

Overview

1. DNA Is the Primary Genetic Material

2. Information Flow from DNA to Protein

3. Control of Gene Expression

4. Basic Tools of Recombinant DNA

5. Fundamental Features of Eukaryotic Genes

6. A New Toolbox for Recombinant DNA

7. Mobile DNA Sequences in the Genome

8. Epigenetic Modifications of the Genome

9. RNAi Regulates Gene Action

FOUNDATIONS OF GENOMICS

Overview

10. Fundamentals of Whole-Genome Sequencing

11. How the Human Genome Was Sequenced

ANALYZING GENOMES

Overview

12. Comparing and Analyzing Genomes

13. From Genome Sequence to Gene Function

HUMAN GENOMICS

Overview

14. Finding Human Disease Genes

15. Understanding the Genetic Basis of Cancer

16. DNA Fingerprinting and Forensics

Figure Credits

Index