Human papillomaviruses (HPV) are a heterogeneous and still growing virus family. Topical research results on the replication cycle and carcinogenic mechanisms allow a better understanding of current prevention strategies. Written by leading experts, this volume of Monographs in Virology provides up-to-date information on the prevention of papillomavirus-induced cancers by prophylactic antiviral vaccines and early detection of precancerous lesions.
A major section covers the tremendous clinical burden due to HPV infections: genital warts and laryngeal papillomas, the most notorious cervical cancer, but also further anogenital and tonsillar cancer, the incidence of which increased steeply during the last decades. Additionally, a section on prevention addresses the subject cytology - new concepts of biomarker development, detection of HPV DNA and RNA as well as their use in primary screening for early detection of precancerous lesions. Finally the book closes with a topical discussion of the most intriguing primary prevention of HPV infection by vaccination.
As new perspectives for the prevention of HPV-related neoplasia raised great public interest, this book will be of value to clinicians and practitioners in gynecology, dermatology, urology and ENT, to pathologists, laboratory physicians, medical students, and public health authorities.
TOC:
Preliminary Pages
I Title Page / Table of Contents / Foreword
Pfister H (ed): Prophylaxis and Early Detection of HPV-Related Neoplasia. Monogr Virol. Basel, Karger, 2012, vol 28, pp I–VIII
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1 Virology and Pathogenesis
Pfister, H.
Pfister H (ed): Prophylaxis and Early Detection of HPV-Related Neoplasia. Monogr Virol. Basel, Karger, 2012, vol 28, pp 1–11
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12 Epidemiology of Mucosotropic Papillomaviruses
Gissmann, L.
Pfister H (ed): Prophylaxis and Early Detection of HPV-Related Neoplasia. Monogr Virol. Basel, Karger, 2012, vol 28, pp 12–18
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Clinical Aspects of Low-Risk HPV Infections
19 Condylomata Acuminata
Gross, G.
Pfister H (ed): Prophylaxis and Early Detection of HPV-Related Neoplasia. Monogr Virol. Basel, Karger, 2012, vol 28, pp 19–29
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30 Recurrent Respiratory Papillomatosis
Wittekindt, C. ; Wagner, S. ; Klussmann, J.P.
Pfister H (ed): Prophylaxis and Early Detection of HPV-Related Neoplasia. Monogr Virol. Basel, Karger, 2012, vol 28, pp 30–37
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Clinical Aspects of High-Risk HPV Infections
38 Cervical Cancer and Intraepithelial Neoplasia
Schneider, A. ; Köhler, C. ; Chiantera, V. ; Vercellino, G.F.
Pfister H (ed): Prophylaxis and Early Detection of HPV-Related Neoplasia. Monogr Virol. Basel, Karger, 2012, vol 28, pp 38–49
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50 Cancer and Intraepithelial Neoplasia of the Vulva and Vagina
Petry, K.U.
Pfister H (ed): Prophylaxis and Early Detection of HPV-Related Neoplasia. Monogr Virol. Basel, Karger, 2012, vol 28, pp 50–57
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58 Penile Cancer and Penile Intraepithelial Neoplasia
Gross, G. ;
Pfister H (ed): Prophylaxis and Early Detection of HPV-Related Neoplasia. Monogr Virol. Basel, Karger, 2012, vol 28, pp 58–71
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72 Anal Cancer and Intraepithelial Neoplasia
Wieland, U. ; Kreuter, A.
Pfister H (ed): Prophylaxis and Early Detection of HPV-Related Neoplasia. Monogr Virol. Basel, Karger, 2012, vol 28, pp 72–78
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79 Tonsillar Cancer
Klussmann, J.P. ; Wagner, S. ; Wittekindt, C.
Pfister H (ed): Prophylaxis and Early Detection of HPV-Related Neoplasia. Monogr Virol. Basel, Karger, 2012, vol 28, pp 79–87
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Diagnosis for Early Detection
88 Cytology
Ikenberg, H.
Pfister H (ed): Prophylaxis and Early Detection of HPV-Related Neoplasia. Monogr Virol. Basel, Karger, 2012, vol 28, pp 88–98
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99 Concepts of Biomarker Development
von Knebel Doeberitz, M. ; Vinokurova, S. ; Reuschenbach, M.
Pfister H (ed): Prophylaxis and Early Detection of HPV-Related Neoplasia. Monogr Virol. Basel, Karger, 2012, vol 28, pp 99–108
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109 Detection of Human Papillomavirus DNA and RNA
Ikenberg, H.
Pfister H (ed): Prophylaxis and Early Detection of HPV-Related Neoplasia. Monogr Virol. Basel, Karger, 2012, vol 28, pp 109–119
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120 Human Papillomavirus Testing in Primary Screening for Cervical Cancer
Petry, K.U.
Pfister H (ed): Prophylaxis and Early Detection of HPV-Related Neoplasia. Monogr Virol. Basel, Karger, 2012, vol 28, pp 120–126
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127 Primary Prevention by Vaccination
Kaufmann, A.M. ; Gissmann, L.
Pfister H (ed): Prophylaxis and Early Detection of HPV-Related Neoplasia. Monogr Virol. Basel, Karger, 2012, vol 28, pp 127–135
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Further Section
136 Author Index
Pfister H (ed): Prophylaxis and Early Detection of HPV-Related Neoplasia. Monogr Virol. Basel, Karger, 2012, vol 28, pp 136
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137 Subject Index
Pfister H (ed): Prophylaxis and Early Detection of HPV-Related Neoplasia. Monogr Virol. Basel, Karger, 2012, vol 28, pp 137–140
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