Zweigstelle	Standorte	Status	Vorbestellungen	Frist	Barcode	Lageplan	Ausleihhinweis
Zweigstelle: Hauptstelle	Standorte: NA-30 175	Status: Verfügbar	Vorbestellungen: 0	Frist:	Barcode: 00191981	Lagepläne: Lageplan	Ausleihhinweis:

Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess great potential as drug targets. They permit highly specific pharmacological interference with defined cellular functions. Drugs targeting such interactions are likely to act with fewer side effects than conventional medication influencing whole cell functions.

 

This book discusses therapeutically relevant protein-protein interactions with a major focus on scaffolding proteins tethering signal transduction processes to defined cellular compartments by direct protein-protein interactions. Recent advances in the development of pharmacological agents interfering with protein-protein interactions are highlighted.

Table of contents

 

Preface.- Part I. Organization of Scaffolds.- Part II. Scaffolding Proteins and Cellular Signalling.- Part III. Cell Type-Specific Anchoring.- Part IV. Interference With Protein-Protein Interaction Sites as a New Pharmacological Concept.