Enzybiotics, by using enzymes to fight bacteria, offer a novel and promising new way to combat infectious diseases. This book presents the state-of-the-art and therapeutic potential of enzybiotics, with a stress on therapeutic applications. The coverage offers a unique combination of medicinal chemistry, microbiology, genetics, and biochemistry. It also addresses the timely topic of bacterial resistance to antibiotics, and provides readers with a novel angle to study and combat infectious diseases.
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PREFACE.
CONTRIBUTORS.
1 ENZYBIOTICS AND THEIR POTENTIAL APPLICATIONS IN MEDICINE (Jan Borysowski and Andrzej Górski).
2 ADVANTAGES AND DISADVANTAGES IN THE USE OF ANTIBIOTICS OR PHAGES AS THERAPEUTIC AGENTS (Patricia Veiga-Crespo and Tomas G. Villa).
3 ENZYBIOTICS AS SELECTIVE KILLERS OF TARGET BACTERIA (Juan C. Alonso and Marcelo E. Tolmasky).
4 PHYLOGENY OF ENZYBIOTICS (Patricia Veiga-Crespo and Tomas G. Villa).
5 BACTERIOPHAGE LYSINS: THE ULTIMATE ENZYBIOTIC (Vincent A. Fischetti).
6 BACTERIOPHAGE HOLINS AND THEIR MEMBRANEDISRUPTING ACTIVITY (María Gasset).
7 ANTI-STAPHYLOCOCCAL LYTIC ENZYMES (Jan Borysowski and Andrzej Górski).
8 MEMBRANE-TARGETED ENZYBIOTICS (María Gasset).
9 DESIGN OF PHAGE COCKTAILS FOR THERAPY FROM A HOST RANGE POINT OF VIEW (Lawrence D. Goodridge).
10 IDENTIFYING PHAGE LYTIC ENZYMES: PAST, PRESENT, AND FUTURE (Jonathan E. Schmitz, Raymond Schuch, and Vincent A. Fischetti).
11 USE OF GENETICALLY MODIFIED PHAGES TO DELIVER SUICIDAL GENES TO TARGET BACTERIA (Lawrence D. Goodridge).
CONCLUDING REMARKS: THE FUTURE OF ENZYBIOTICS (Patricia Veiga-Crespo and Tomas G. Villa).
INDEX.
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Verfasserangabe:
edited by Tomas G. Villa and Patricia Veiga-Crespo
Jahr:
2010
Verlag:
Hoboken, NJ, Wiley
Aufsätze:
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Interessenkreis:
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Monographien
ISBN:
9780470376553
2. ISBN:
0-470-37655-4
Beschreibung:
X, 284 S. : graph. Darst.
Sprache:
englisch||
Fußnote:
Literaturangaben
Mediengruppe:
Ausleihbestand