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Cell Press Reviews: Cancer Therapeutics informs, inspires, and connects cancer researchers at all stages in their careers with timely, comprehensive reviews written by leaders in the field and curated by Cell Press editors. The publicatio offers a broad view of some of the most compelling topics in cancer therapeutics including:

 

Genetic approaches for personal oncology

Targeting epigenetic dysregulation and protein interaction networks

Vaccines and antibodies in cancer immunotherapy

Tumor heterogeneity and chemotherapy resistance

Tumor associated macrophages in anticancer treatment

Contents:

1) The evolving war on cancer; Daniel A. Haber, Nathanael S. Gray and Jose Baselga; Cell

2) Can we deconstruct cancer, one patient at a time? C. Anthony Blau and Effie Liakopoulou; Trends in Genetics

3) The genetic basis for cancer treatment decisions; Janet E. Dancey, Philippe L. Bedard, Nicole Onetto and Thomas J. Hudson; Cell

4) Cancer epigenetics: From mechanism to therapy; Mark A. Dawson and Tony Kouzarides; Cell

5) Converting cancer therapies into cures: Lessons from infectious diseases; Michael S. Glickman and Charles L. Sawyers; Cell

6) Antibody-based immunotherapy of cancer; Louis M. Weiner, Joseph C. Murray and Casey W. Shuptrine; Cell

7) Macrophage regulation of tumor responses to anticancer therapies; Michele De Palma and Claire E. Lewis; Cancer Cell

8) Recombinant viral vaccines for cancer; Ryan Cawood, Thomas Hills, Suet Ling Wong, Aliaa A. Alamoudi, Storm Beadle, Kerry D. Fisher and Leonard W. Seymour; Trends in Molecular Medicine

9) Dynamics of targeted cancer therapy; Ivana Bozic, Benjamin Allen and Martin A. Nowak; Trends in Molecular Medicine

10) Targeting protein-protein interactions as an anticancer strategy; Andrei A. Ivanov, Fadlo R. Khuri and Haian Fu; Trends in Pharmacological Sciences

11) Targeting the RAS pathway in melanoma; Zhenyu Ji, Keith T. Flaherty and Hensin Tsao; Trends in Molecular Medicine

12) Targeting tumor cell motility as a strategy against invasion and metastasis; Alan Wells, Jelena Grahovac, Sarah Wheeler, Bo Ma and Douglas Lauffenburger; Trends in Pharmacological Sciences

13) The Valley of Death in anticancer drug development: a reassessment; David J. Adams; Trends in Pharmacological Sciences

14) Metformin and cancer: from the old medicine cabinet to pharmacological pitfalls and prospects; Arian Emami Riedmaier, Pascale Fisel, Anne T. Nies, Elke Schaeffeler and Matthias Schwab; Trends in Pharmacological Sciences

15) Curing APL through PML/RARA degradation by As2O3; Valerie Lallemand-Breitenbach, Jun Zhu, Zhu Chen and Hugues de Th?©; Trends in Molecular Medicine

16) A snapshot of chemoresistance to PARP inhibitors; Alberto Chiarugi; Trends in Pharmacological Sciences