Zweigstelle	Standorte	Status	Vorbestellungen	Frist	Barcode	Lageplan	Ausleihhinweis
Zweigstelle: Hauptstelle	Standorte: ME-20 82	Status: Verfügbar	Vorbestellungen: 0	Frist:	Barcode: 00196274	Lagepläne: Lageplan	Ausleihhinweis:

Aus erster Hand berichten die Autoren der Beiträge dieses Bandes, mit welchen Strategien in der kommerziellen Forschung nach Wirkstoffen gegen Infektionskrankheiten gesucht wird. Dabei konzentrieren sie sich in erster Linie auf Parasitosen, berücksichtigen aber auch bakterielle Infektionen. Hochinteressante Informationen, die man in dieser Form nirgends findet!

 

Aus dem Inhalt

Preamble

Editor Preface

PART I Drug Discovery Approaches

1 Target identification and mechanism-based screening for anthelmintics: Application of veterinary antiparasitic research programmes to search for new antiparasitic drugs for human indications

2 Anthelmintic resistance as a guide to the discovery of new drugs?

3 Drug discovery for neglected diseases: view of a public-private partnership

4 Bioinformatics and Chemoinformatics: Key Technologies in the Drug Discovery Process

5 Target identification and validation in anti parasitic drug discovery

6 Selective Drug Targets in Parasites

7 Lessons Learned From Target Based Lead Discovery

8 Approaches towards Antiparasitic Drug Candidates for Veterinary Use

9 Learning to Relate Structural Space with Property Space

10 Recruiting the Host Defense Mechanisms: Roles for Vaccines and Chemotherapeutics

PART II Protozoan Parasites

11 Proteases of Parasitic Protozoa - Current Status and Validation

12 In Search of Trypanocidal Drugs

13 Trypanosomatid protein kinases as potential drug targets

14 Targeting the malaria kinome; discovering kinase inhibitors as novel antimalarial agents

15 Malaria and anti-malarials - a focused view

PART III Multicellular Parasites

16 Chemotherapeutic development strategies for schistosomiasis

17 Searching new Anti-Parasitics in the Virtual Space

18 Cyclooctadepsipeptides - an anthelmintically active class of compounds exhibiting a novel mode of action

19 Chemical Optimization of Anthelmintic Compounds - a Case Study

PART IV Bacteria

20 Pathogenomics: identification of novel drug targets and vaccine candidates in bacteria

21 Tuberculosis Drug Discovery: Issues, Gaps and the Way Forward

22 Decreasing the number of gaps in the draft assembly of the Mannheimia haemolytica M7/2 genome sequence

23 Total synthesis and configurational assignment of pasteurestin A and B, a natural product with antimicrobial acitivty on Pasteurellaceae