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Progress in the Chemistry of Organic Natural Products Volume 115

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Year: [2021]
Publisher: Cham, Springer Nature Switzerland AG
Series: Progress in the chemistry of organic natural products; 115
Media group: Serien
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Content

This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.

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Statement of Responsibility: A. Douglas Kinghorn, Heinz Fallk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch, editors
Year: [2021]
Publisher: Cham, Springer Nature Switzerland AG
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ISBN: 9783030648527
ISBN (2nd): 3030648524
Description: vi, 203, 4 Seiten, Diagramme, Illustrationen
Series: Progress in the chemistry of organic natural products; 115
Tags: Naturstoffe allgemein
Language: Englisch
Media group: Serien